ACRP Seminar – COVID19 & the Effect on Clinical/Non-Clinical Studies

Director of Experiential Education , Department of Clinical and Administration Sciences

Education:
Doctor of Pharmacy from Midwestern University
Bachelor of Science from the University of California in Physics and Psychology

Bio:
An experienced Ambulatory Community Pharmacist with 20 years in practice with pharmacy management, community practice, and medication therapy management. Prior to joining AUHS, Dr. Transon Nguyen was in pharmacy practice working with independent pharmacies and non-profit clinics in drug information, developing formularies and procedures for drug management and regulatory compliance. He has managed multiple community pharmacies and has taught numerous pharmacists and interns.
Dr. Transon Nguyen has been actively involved in educating school children and seniors on medication safety, adherence, basic self-care and healthcare. He is an active community volunteer for the Red Cross and the city of Irvine’s Community Emergency Response Team.
Dr. Transon Nguyen currently serves as mentor for the students of the non-profit Orange County Community Health Affiliation and he has an ongoing working relationship with the non-profit Lestonnac Free Clinic since 2005.

Publications
Nguyen, Transon. Apothecary Anecdotes: Old Tales from The Pharm. Amazon Publishing, 2021.
Nguyen, Transon. Nowhere: Steps along the journey from nowhere to now here. Amazon Publishing, 2021.

Adjunct Professor, Clinical and Administrative Sciences

Education
PharmD – Washington State University, College of Pharmacy and Pharmaceutical Sciences, Spokane, WA
Pharmacy Academia Fellowship – Washington State University, College of Pharmacy and Pharmaceutical Sciences, Spokane, WA
BS in Chemistry – University of Nevada, Reno, Reno, NV

Bio
Dr. Zhang obtained a Bachelor of Science in Chemistry from the University of Nevada, Reno and his PharmD from Washington State University, College of Pharmacy and Pharmaceutical Sciences (WSU). Upon graduation, he continued a two-year fellowship in pharmacy academia at WSU before coming to AUHS. His clinical background includes long-term care, home health care, and pharmacy academia. His interests include improving students through soft skill engagement and using learning activities such as games to improve student performance.

Publications
Zhang B., Kim, S., Xiao, Y., Damman, C., Kelly, K., Fitzpatrick, D., Anderson, C., Ritchie, M., Bray, B., Stewart,
A., Daoud, S., Remsberg, C. A Student Initiative to Implement Peer-led Study Groups for a Pharmacogenomics
Course: Evaluation of Student Performance and Perceptions. CPTL. 2020; 12(5): 549-557. doi: 10.1016/j.cptl.2020.01.013

Zhang, B., Li, F., Chen, Z., Shrivastava, I.H., Gasanoff, E.S., Dagda, R.K. Naja mossambica mossambica
Cobra Cardiotoxin Targets Mitochondria to Disrupt Mitochondrial Membrane Structure and Function. Toxin. 2019; 11(3): 152. Doi: 10.3390/toxins11030152

Dagda, R.K., Gasanov, S., Shrivastava, I.H., Israilov, F.S., Kim, A.K., Rylova, K.A., Zhang, B. Naja naja
oxiana Cobra Venom Cytotoxins CTI and CTII Disrupt Mitochondrial Membrane Integrity: Implications for Basic
Three-Fingered Cytotoxins. PLOS One. 2015; 10(6): e0129248. doi: 10.1371/journal.pone.0129248

Dagda, R.K., Gasanov, S., Zhang, B., Welch, W., Rael, E.D. Molecular Models of the Mojave Rattlesnake
(Crotalus scutulatus scutulatus) Venom Metalloproteinases Reveal a Structural Basis for Differences in
Hemorrhagic Activities. J Biol Phys. 2014: 40(20: 193-216. doi: 10.1007/s10867-013-9339-3

Adjunct Professor of Clinical and Administrative Sciences

Education:
Doctor of Pharmacy from Chapman University
Bachelor of Science from the University of California in Biological Sciences
Bio:
Dr. Jimmy Nguyen graduated with his PharmD from Chapman University as the first inaugural class. Dr. Nguyen graduated his class as Rho Chi, top 10%. While there he was a Board Member of California Health Science Systems and other distinguished groups in the accreditation process of his school.
From there, he worked as an outpatient pharmacist for Rite Aid Pharmacy then moved on to CVS Pharmacy. While working with CVS, he was able to lead his own team in COVID vaccine clinics, traveling to different sites every day to administer vaccines. There he learnt the importance of charisma, leadership and organization. Currently he is a part of the Emerging Leader Program with CVS while being an adjunct clinical professor with AUHS.

Joseph Kunchandy, MPharm, PhD, RPh

Adjunct Professor of Clinical & Administrative Sciences
Education

B. Pharm | College of Pharmaceutical Sciences, Trivandrum, Kerala, India
M. Pharm | Center for Advanced Pharmaceutical Sciences, Panjab University, Chandigarh, India
Ph.D. in Neuropharmacology | Panjab University, Chandigarh, India
Post-Doctoral Fellowship in Pediatric Neuropharmacology | UCLA School of Medicine, Los Angeles, CA
Post-Doctoral Fellowship in Medicinal Chemistry & Cell Culture | College of Pharmacy, University of Oklahoma Health Sciences Center, Oklahoma City, OK
Bio

Dr. Joseph Kunchandy brings forth acute care hospital management, clinical and retail-based pharmacy, professional research experience, and teaching experience to the School of Pharmacy at American University of Health Sciences. His range of clinical and research experiences are based on years of acute care hospital pharmacy management, retail-based pharmacy, and application and knowledge of neuropharmacology research. Dr. Kunchandy also participates as a consultant in the hospital accreditation process in areas of medication, such as the management process.

Jonathan Coffman, PhD, MBA
Associate Professor of Microbiology & Immunology

Education
PhD University of Tennessee Health Science Center, Memphis, TN, USA

MBA Nova Southeastern University, Davie, FL, USA
BA Southeastern University, Lakeland, FL, USA

Bio
Dr. Coffman has been teaching Medical Microbiology, Immunology and Genetics for the last few decades and has supported his students with research, poster presentations and publications.  Dr. Coffman has developed several biomedical science programs along with courses in health-care administration, and he has also worked with several institutions on accreditation, programmatic assessments, student recruitment and marketing strategies.

Published Research

Shaw, G and Coffman, J. Components of an Evidence-Based Analytic Rubric for Use in Medical School Admissions. JAPMA 2017, Vol. 107, No. 1, pp. 65-71.

Noriega B, Sanchez-Gonzalez, M, Salyakina D. and Coffman J. Understanding the Impact of Omega-3 Rich Diet on the Gut Microbiota. Case Reports in Medicine, Volume 2016 (2016), Article ID 3089303.

Whalen D, Molnar D, Milne F., Schwal L., Hackett V. and Coffman J. Flu vaccine experiences and beliefs influence vaccination decision making more than knowledge. F1000Research 2014, 3:224.

Strong T, Dowd S, Gutierrez A and Coffman, J. Amplicon pyrosequencing and ion torrent sequencing of wild duck eubacterial microbiome from fecal samples reveals numerous species linked to human and animal diseases, F1000Research 2013, 2:224

Murray PE, Coffman JA, Godoy-Garcia F. Dentists could be leading bioengineers of 21st century.  Today’s FDA. 2005; 17: 17-8.

Murray, P.E., Coffman, J.A. and Garcia-Godoy, F. (2004). Pulp Responses to Remaining Dentin Thickness. Today’s FDA. July. 17-19.

Kathleen H. Cox, Rajendra Rai, Mackenzie Distler, Jon R. Daugherty, Jonathan A. Coffman and Terrance G. Cooper (2000). Saccharomyces cerevisiae GATA Sequences Function as TATA Elements during Nitrogen Catabolite Repression and When Gln3p Is Excluded from the Nucleus by Overproduction of Ure2p. J. Biol. Chem. 275: 17611-17618.

Research and Areas of Interest
Vaccination Decision Models
Oral and Intestinal Microbiota Studies
Opioid Use Order in Medical Education

Carol Yuan, BS, Pharm.D, BCPP, APh

Adjunct Assistant Professor, Department of Clinical and Administration Sciences (Adjunct/Part-time)

Education

Doctor of Pharmacy – Western University of Health Sciences

PGY-2 Psychopharmacology & Clinical Psychiatry, Western University of Health Sciences/Aurora Charter Oak Hospital

B.S. Biological Sciences, CSU East Bay

Teaching Certificate obtained from PGY-2 training – Western University of Health Sciences

Biography

Dr. Yuan currently serves as Adjunct Assistant Professor in the Clinical and Administrative Department at the American University of Health Sciences School of Pharmacy. Dr. Yuan comes to AUHS with extensive pharmacy practice and pharmacy consulting experiences in both psychiatric hospital and retail pharmacies, specializing in adolescent and adult clinical psychiatry and psychopharmacology.

As an experienced clinical pharmacist clinician, Dr. Yuan works as a Director of Pharmacy and clinical pharmacist in an inpatient psychiatric hospital for over 11 years. Prior to working as a clinical pharmacist in a hospital setting, she also had many years of experiences working in the retail pharmacies as a pharmacist and pharmacy manager. Dr. Yuan has been precepting pharmacy technician students, Pharm.D. students, and Pharmacy residents from multiple pharmacy schools for over 13 years.

Dr. Yuan is well experienced in pharmacy management, both in the acute care psychiatric hospital setting and retail setting. She is highly proficient in performance management, clinical protocol development, policy and procedure development, best practices implementation, and students/pharmacy residents developments.

Courses Taught

Personality Disorder

ADHD

Glaucoma

Publications

1. Carol Yuan, Ji Haeng Heo, Busuyi Olotu, Annie Hiu, Michael Pondrom, Maria Arredondo. “Comparison of Long-Acting Injectables in the Treatment of Mental Illness to Prevent Hospital Readmission in Less Than 30 days After Discharge: A Retrospective Study. Poster presented in the CPNP Annual Meeting, April 2019. Salt Lake City, NV, USA.

2. Shankar, G.S., Yuan, X.J., “Comparative study of Zolpidem and Hypnotic Benzodiazepines Related Falls in Acute Psychiatric Hospital.” Abstract accepted by CPNP, Florida 2012.

3. Shankar, G.S., Yuan, X.J., “Evaluation of the Substance Detoxification Protocols in an Acute Psychiatric Hospital.” Abstract accepted by CPNP, Florida 2012.

4. Shankar, G.S., Luu, Haiau, Yuan, X.J., “Impact of Pharmacists in Achieving Therapy Goals, Medication Adherence, and Patient Satisfaction in Patients with Psychiatric Illnesses in an Outpatient Setting.” Abstract accepted by CPNP, Florida 2012.

5. Hugo R. Arias, Avraham Rosenberg, Katarzyna M. Targowska-Duda, Dominik Feuerback, Xiaojuan Yuan, Krzysztof Jozwiak, Ruin Moaddel, Irving W. Wainer. “Interaction of Ibogain with Human α3β4-Nicotinic Acetylcholine Receptors in Different Conformational States.” The International Journal of Biochemistry & Cell Biology 42 (2010) 1525-1535

6. Yuan, X.J., Guo, W., Dong, F., Lin, SH., Chu, K., Nate, C., G.S Shankar “A Cross Country Study of the Effect of Three Dibenzodiazepines: clozapine, quetiapine and olanzapine on Thyroid Function in Patients with Schizophrenia.” Published in the Journal of Pharmacy Practice, May 2010.

7. Shankar, G.S., Yuan, X.J., “Monitoring and Counseling of Metabolic Complications and Antipsychotic Pharmacotherapy.” published on Premier Education Solution, 2010.

8. “A Novel Model for Community Pharmacy Practice Residency to Promote Medication Therapy Management.” CAPSLEAD TEAM – XJ Yuan, A Khosho, H Umenoto, S Yang , HT Li, K Mai, L Kaw, B Joy de Guia, J Wong, H.P Nguyen, E Gupta E, K Hess K, S Shimomura, and SF Wong. Poster Presented in:

– California Pharmacists Association Annual Meeting Outlook 2008, February 7-10, 2008 in  Sacramento, California.

– 42nd ASHP Midyear Clinical Meeting December 2-6, 2007 in Las Vegas, NV.

– CSHP Seminar October, 2007 in Palm Spring, California

9. Yuan, X.J., Arias, H.R., Bhumireddy, P., Glick, S.D., and Kuehne, M.E. “Characterization of the 18-Methoxycoronaridine Binding Site on the Nicotinic Acetylcholine Receptor.” J.Neurochem. 2007; 102, (Suppl.1), 271 (Abs. P.424)

10. Yuan, X.J., Arias, H.R., Bhumireddy, P., Glick, S.D., and Kuehne, M.E. “Characterization of the 18-Methoxycoronaridine Binding Site on the Nicotinic Acetylcholine Receptor.” 46th Annual Meeting of the American Society for Cell Biology, San Diego, CA, USA, Dec. 9-13, 2006

Dr. Zafeer Fazelbhoy PharmD, M.S, BCPS

Assistant Professor of Clinical and Administrative Sciences (Adjunct/Part-time)

Education-

PharmD- Western University of Health Sciences, CA

M.S- Medical College of Virginia, VA

B.S- University of California- Los Angeles, CA

Bio- Dr. Fazelbhoy completed his PharmD from Western University of Health Sciences and his Master of Science degree from the Medical College of Virginia. He is a registered pharmacist in the state of California and is also licensed as an Advanced Practice Pharmacist. He is Board Certified in Pharmacotherapy and currently works as a Clinical Pharmacist at Aurora Charter Oak Hospital in Covina, CA. He is also AAHIVP certified and has worked in the field of HIV medicine in San Francisco and Los Angeles.

Areas of Experience-Inpatient Care, Outpatient Care, Psychiatry and HIV medicine.

Scholarship Interests- Research in Psychiatry, Addiction Medicine and Internal Medicine.

Research-

1. Hon Wai Koon, David Shih, Iordanis Karagiannides, Dezheng Zhao, Fazelbhoy ZA, Tressia Hing, Hua Zu, Bao Lu, Norma Gerard, Charlabos Pothoulakis. Substance P modulates chronic inflammation induced colonic fibrosis. Am J Pathology. July 2010

2. Fazelbhoy ZA, Zhao B, Song J, Bie J and Ghosh S. Role of Cholesterol Ester Hydrolase (CEH) mediated cholesterol mobilization on atherosclerotic plaque stability. Arteriosclerosis, Thrombosis and Vascular Biology. June 2009. ABSTRACT.

3. Ghosh SS, Massey HD, Krieg R, Fazelbhoy ZA, Ghosh S, Sica DA, Fakhry I, Gehr TWB. Curcumin ameliorates renal failure in 5/6 nephrectomized rats: The role of inflammation. Am. J Physiology – Renal Physiol. Feb 2009.

Christine Han, PharmD

Professor of Clinical and Administrative Sciences (Adjunct/Part-time)

Bio:
Dr. Han brings over 10 years of community practice, pharmacy management, and medication therapy management experiences to the AUHS School of Pharmacy. Prior to joining AUHS, Dr. Han was in pharmacy practice working closely with independent pharmacies and physicians in developing procedures for drug management and regulatory compliance. She has managed multiple pharmacies and has taught numerous pharmacist interns and pharmacists who have successfully become pharmacy managers. Dr. Han has been actively involved in educating seniors on medication adherence, chronic disease states, and Medicare Part D prescription drug benefits. She also provides medication management in various senior facilities. Dr. Han currently serves as a member for the California Korean American Pharmacist Association.

Education:
PharmD – University of Hawaii, Hilo
BS (Psychobiology) – University of California, Los Angeles

Areas of Expertise:
Community Practice, Ambulatory Care

Courses Taught:
U.S. Healthcare
Self-Care Pharmacotherapy and Alternative Therapy
Pharmacy Practice Management
Pharmacy Law
Psychosocial Aspect of Healthcare

Scholarship Interests:
Comprehensive Medication Management, Geriatrics, Innovative Teaching

Publications:
Chong MT and Han CSH. “Integration of a Business Plan Project within a Pharmacy Management and Marketing course for Pharmacy Students in a Doctor of Pharmacy Program.” J Am Pharm Assoc 2013;53:2:89-90
Chong MT and Han CSH. “Student’s Perception and Feedback on A Management and Marketing course offered in a PharmD Program.” 11th Asian Conference on Clinical Pharmacy Abstracts Publications, Manila. June 2011,“Target Your Heart,” Target Corporation “Wellness” Business Plan Competition Finalist, University of Hawaii, Hilo College of Pharmacy. Nov 2011,

Alamdar Hussain, Ph.D.

Assistant Dean of Student Affairs and Admission / Associate Professor of Pharmaceutical Sciences

Education
Ph.D., Pharmaceutics, Texas Tech University Health Sciences Center, Amarillo, TX
B.S. in Pharmacy, Kakatiya University, Warangal, India

Bio
Dr. Hussain received his Ph.D. in Pharmaceutics from the Graduate School of Biomedical Sciences at Texas Tech University Health Sciences Center in Amarillo, TX, and his B.S. in Pharmacy from Kakatiya University in India. Prior to joining AUHS, Dr. Hussain worked as Assistant Professor of Pharmaceutical Sciences at the Universities of Louisiana and Oklahoma. He has taught both professional pharmacy and graduate students various courses including but not limited to Pharmaceutics, Compounding Pharmacy, Pharmacokinetics, Physical Pharmacy, Advanced Drug Delivery and Targeting, Pharmaceutical Technology, Medical Microbiology, and Biotechnology. He has also mentored several M.S. and Ph.D. students throughout his career.

Dr. Hussain’s research interest primarily focuses in the field of inhalation protein and peptide drug delivery. He is currently investigating ways to improve absorption of drugs by non-invasive routes in laboratory animals and understand mechanisms of macromolecular drug transport in vitro. Dr. Hussain is also passionate about student learning and implements novel methods of teaching and learning in classroom and laboratory. He is actively pursuing the arena of Scholarship of Teaching and Learning after joining AUHS in 2020.

With regard to his leadership experience, Dr. Hussain is a former Chair of the Department of General Education at AUHS. Currently, he serves as the Assistant Dean for Student Affairs and Admission for the School of Pharmacy.

Selected Publications (Since 2014)

E. Nguyen, S. Kim, M. Islam, Y. Chang, J. Aoyagi, A. Hussain (2022). An entrepreneurial activity implementation and assessment among pharmacy students amid the COVID-19 pandemic lockdown. Pharmacy Education, 22(1):16-22.

A. Hussain, H. Chau, H. Bang, L. Meyer, M. Islam (2021). Performance of pharmacy students in a communications course delivered online during the COVID-19 pandemic. American Journal of Pharmaceutical Education, 85(10): Article 8617.

A. Hussain (2021). Implementation of online assignment submission with instant feedback in a pharmacy course. Pharmacy Education, 21(1):45-50.

D. Raghuvanshi, G. Nkepang, A. Hussain, H. Yari, V. Awasthi (2017). Stability studies on an anticancer drug 4-(3.5-bis (2-chlorobenzylidene)-4-oxo-piperidine)-4-oxo-2-butenoic acid (Clefma) using a stability indicating HPLC method. Journal of Pharmaceutical Analysis, 7(1):1-9.

G. Rao, A. Hedrick, V. Yadav, J. Xie, A. Hussain, V. Awasthi (2015). The brain metabolic activity after resuscitation with liposome-encapsulated hemoglobin in a rat model of hypovolemic shock. Journal of Cerebral Blood Flow Metabolism, 35(9):1528-36.

K. Amancha, A. Hussain (2015). Effect of protease inhibitors on pulmonary bioavailability of therapeutic proteins and peptides in the rat. European Journal of Pharmaceutical Sciences, 20(68):1-10.

V. Yadav, A. Hussain, J Xie, S. Kosanke, V. Awasthi (2015). The salutary effects of diphenyldifluoroketone EF24 in liver of a rat hemorrhagic shock model. Scandinavian Journal of Trauma Resuscitation and Emergency Medicine, 23:8.

V. Yadav, A. Hussain, K. Sahoo, V. Awasthi (2014). Remediation of hemorrhagic shock-induced intestinal barrier dysfunction by treatment with diphenyldihaloketones, EF24 and Clefma. Journal of Pharmacology and Experimental Therapeutics, 351(2):413-422.

K. Amancha, S. Balkundi, Y. Lvov, A. Hussain (2014). Pulmonary sustained release of insulin from microparticles composed of polyelectrolyte layer-by-layer assembly. International Journal of Pharmaceutics, 466(1-2)96-108.

Co-Founder Genom Global Venture (A Division of Genom LIfe Sciences)
Mr. Kal Chatto, is an entrepreneur and business executive with 30 plus years’ worth of expertise and experience in the biotech & pharmaceutical world. Mr. Chatto is an Adjunct Professor at Chapman University School of Pharmacy. He was also an Adjunct Visiting Professor for 4 years (3/’13-3/’17), Manipal College of Pharmaceutical Sciences, Manipal University ranked #1 in India.
In 2005, as the Co-Founder and Board Member, Mr. Chatto helped in building and shaping Manipal Acunova, which acquired Ecron, a top European Contract Research Organization (CRO) and became Ecron Acunova (EA), one of the most successful international CROs (Privately held). Ecron Acunova won the prestigious Proximire Award and Bio-Excellence Award and EA was acquired by Take Solutions in FY 2015- 2016. In 2007, he became the Co-Founder and Board member of Avitacor, LLC, a CRO focusing on Latin America, which was sold to a private investors group in Mexico.
In 1988, Mr. Chatto was recruited from the Glaxo Pharmaceuticals (now GSK) in Marketing and Sales Leadership Team to be one the first 9 Amgen Founding Marketing and Sales leaders to launch and commercialize a major breakthrough biotech products, Epogen, Neupogen, Aranesp, Neulasta and Enbrel. Mr.Chatto relentlessly contributed to Amgen’s paramount success (market cap from $100 Million to $75.17 Billion in Q4’04) in becoming one the best biotech companies worldwide by improving values for patients, payers & providers, and stockholders.
Mr. Chatto was Co-Chair of the Host Committee for the 2004 FIP World Congress, New Orleans, U.S.A. In 2005, Mr. Chatto was awarded the “FIP Distinguished Service Award” by the International Pharmaceutical Federation (FIP) in recognition of his exceptional and distinguished contribution to FIP. Recognized globally, the award honors outstanding achievers who inspire others with their vision and leadership. Mr.Chatto also served on the board of leading professional organizations such as Federation of International Pharmacy (FIP) for Education and Research, American College of Clinical Pharmacy (ACCP) Research Institute as well as key pharmacy schools at the University of Arizona, University of Wisconsin, University of Tennessee, and USC.
Mr. Chatto received his B.Pharm from IIT (B.H.U) and M.S. in Pharmacy Administration from Long Island University, New York. He also completed Executive Management Programs from Marshall School of Business, USC, and Anderson School of Management at UCLA

Education:
Doctor of Pharmacy, California Northstate University, Sacramento, CA
B.S in Pharmacology, University of California Santa Barbara

Bio:
Dr. Deng is an assistant professor at American University of Health Sciences. He received his Doctor of Pharmacy degree from California Northstate University College of Pharmacy in Sacramento, California. He completed his PGY1 residency in Community Pharmacy Practice with the University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences. After residency, Dr. Deng completed an Ambulatory Care and Academic Fellowship with Purdue University College of Pharmacy in West Lafayette, Indiana. Prior to this appointment, Dr. Deng has served as faculty at the California Northstate University College of Pharmacy, and practices at Wellspace Health as an Ambulatory Care Pharmacist and Preceptor. His primary research interests include transitions of care, primary care in medically under-served areas, and teaching and learning.

Publication:
Deng B, Fenn NEIII, Plake KS. Impact of a teaching objective clinical examination (TOSCE) on student
confidence in a patient care skills laboratory. Currents in Pharmacy Teaching and Learning 2019; 11:
145-154

Deng B, Kroehl ME, Carter EA, Thompson AM, Perica K, Trinkley KE. Improving Post Discharge
Medication Adherence: A Collaboration Between an Academic Medical Center and a Community
Pharmacy Chain. J Basic Clin Pharm 2017; 8: 116-120.

Dr. Nhung Xuan Hong Le is an Assistant Professor in the Department of Pharmaceutical Science (Adjunct/Part-time).

Research Interests

The focus of my previous work was centered around biocomplexity and how our immune system communicates with our microbiome, as well as how these interactions affect female reproductive disorders such as endometriosis and preterm birth. Thus, as my next step in my career, I want to continue to focus on using molecular biology techniques in order to gain a mechanistic understanding of the interactions between the immune system and mucosal microbial dynamics.

Molecular and Cellular Biological Techniques

Quantitative PCR

ELIZA’s

FACs

Immunohistochemistry

Western Blot

Mammalian Cell Culture

Microbiome Bioinformatics

Education and training

2016 – 2021      Ph.D., Medical Microbiology, Immunology and Cell Biology, Southern Illinois University School of Medicine

2014 – 2016      M.S., Public Health, Southern Illinois University Carbondale

2009 – 2010      M.S., Epidemiology, Washington University in St. Louis

2004 – 2008      B.A., Biochemistry, Westminster College

Peer-reviewed Publications

1. Le N, Cregger M, Brown V, Loret de Mola J, Bremer P, et al. (2021)Association of microbial dynamics with urinary estrogens and estrogen metabolites in patients with endometriosis. PLOS ONE 16(12): e0261362. https://doi.org/10.1371/journal.pone.0261362
2. Le NXH, Loret de Mola JR, Bremer P, Groesch K, Wilson T, Diaz-Sylvester P, Braundmeier-Fleming AG. Alteration of systemic and uterine endometrial immune populations in patients with endometriosis. Am J Reprod Immunol. 2021 Mar;85(3):e13362. doi: 10.1111/aji.13362. Epub 2020 Oct 29. PMID: 33070438.
3. Brazel DM, Jiang Y, Hughey JM, Turcot V, Zhan X, Gong J, Batini C, Weissenkampen JD, Liu M; CHD Exome+ Consortium; Consortium for Genetics of Smoking Behaviour, Barnes DR, Bertelsen S, Chou YL, Erzurumluoglu AM, Faul JD, Haessler J, Hammerschlag AR, Hsu C, Kapoor M, Lai D, Le N, de Leeuw CA, Loukola A, Mangino M, Melbourne CA, Pistis G, Qaiser B, Rohde R, Shao Y, Stringham H, Wetherill L, Zhao W, Agrawal A, Bierut L, Chen C, Eaton CB, Goate A, Haiman C, Heath A, Iacono WG, Martin NG, Polderman TJ, Reiner A, Rice J, Schlessinger D, Scholte HS, Smith JA, Tardif JC, Tindle HA, van der Leij AR, Boehnke M, Chang-Claude J, Cucca F, David SP, Foroud T, Howson JMM, Kardia SLR, Kooperberg C, Laakso M, Lettre G, Madden P, McGue M, North K, Posthuma D, Spector T, Stram D, Tobin MD, Weir DR, Kaprio J, Abecasis GR, Liu DJ, Vrieze S. Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use. Biol Psychiatry. 2019 Jun 1;85(11):946-955. doi: 10.1016/j.biopsych.2018.11.024. Epub 2018 Dec 6. Pubmed PMID:30679032
4. Erzurumluoglu AM, Liu M, Jackson VE, Barnes DR, Datta G, Melbourne CA, Young R, Batini C, Surendran P, Jiang T, Adnan SD, Afaq S, Agrawal A, Altmaier E, Antoniou AC, Asselbergs FW, Baumbach C, Bierut L, Bertelsen S, Boehnke M, Bots ML, Brazel DM, Chambers JC, Chang-Claude J, Chen C, Corley J, Chou YL, David SP, de Boer RA, de Leeuw CA, Dennis JG, Dominiczak AF, Dunning AM, Easton DF, Eaton C, Elliott P, Evangelou E, Faul JD, Foroud T, Goate A, Gong J, Grabe HJ, Haessler J, Haiman C, Hallmans G, Hammerschlag AR, Harris SE, Hattersley A, Heath A, Hsu C, Iacono WG, Kanoni S, Kapoor M, Kaprio J, Kardia SL, Karpe F, Kontto J, Kooner JS, Kooperberg C, Kuulasmaa K, Laakso M, Lai D, Langenberg C, Le N, Lettre G, Loukola A, Luan J, Madden PAF, Mangino M, Marioni RE, Marouli E, Marten J, Martin NG, McGue M, Michailidou K, Mihailov E, Moayyeri A, Moitry M, Müller-Nurasyid M, Naheed A, Nauck M, Neville MJ, Nielsen SF, North K, Perola M, Pharoah PDP, Pistis G, Polderman TJ, Posthuma D, Poulter N, Qaiser B, Rasheed A, Reiner A, Renström F, Rice J, Rohde R, Rolandsson O, Samani NJ, Samuel M, Schlessinger D, Scholte SH, Scott RA, Sever P, Shao Y, Shrine N, Smith JA, Starr JM, Stirrups K, Stram D, Stringham HM, Tachmazidou I, Tardif JC, Thompson DJ, Tindle HA, Tragante V, Trompet S, Turcot V, Tyrrell J, Vaartjes I, van der Leij AR, van der Meer P, Varga TV, Verweij N, Völzke H, Wareham NJ, Warren HR, Weir DR, Weiss S, Wetherill L, Yaghootkar H, Yavas E, Jiang Y, Chen F, Zhan X, Zhang W, Zhao W, Zhao W, Zhou K, Amouyel P, Blankenberg S, Caulfield MJ, Chowdhury R, Cucca F, Deary IJ, Deloukas P, Di Angelantonio E, Ferrario M, Ferrières J, Franks PW, Frayling TM, Frossard P, Hall IP, Hayward C, Jansson JH, Jukema JW, Kee F, Männistö S, Metspalu A, Munroe PB, Nordestgaard BG, Palmer CNA, Salomaa V, Sattar N, Spector T, Strachan DP; Understanding Society Scientific Group, EPIC-CVD, GSCAN, Consortium for Genetics of Smoking Behaviour, CHD Exome+ consortium, van der Harst P, Zeggini E, Saleheen D, Butterworth AS, Wain LV, Abecasis GR, Danesh J, Tobin MD, Vrieze S, Liu DJ, Howson JMM. Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci. Mol Psychiatry. 2019 Jan 7. doi: 10.1038/s41380-018-0313-0. Pubmed PMID:30617275
5. Wetherill L, Agrawal A, Kapoor M, Bertelsen S, Bierut LJ, Brooks A, Dick D, Hesselbrock M, Hesselbrock V, Koller DL, Le N, Nurnberger JI Jr, Salvatore JE, Schuckit M, Tischfield JA, Wang JC, Xuei X, Edenberg HJ, Porjesz B, Bucholz K, Goate AM, Foroud T. Association of substance dependence phenotypes in the COGA sample. Addict Biol. 2015 May;20(3):617-27. doi: 10.1111/adb.12153. Epub 2014 May 16. Pubmed PMID:24832863
6. Kapoor M, Wang JC, Wetherill L, Le N, Bertelsen S, Hinrichs AL, Budde J, Agrawal A, Almasy L, Bucholz K, Dick DM, Harari O, Xiaoling X, Hesselbrock V, Kramer J, Nurnberger JI Jr, Rice J, Schuckit M, Tischfield J, Porjesz B, Edenberg HJ, Bierut L, Foroud T, Goate A. Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families. Drug Alcohol Depend. 2014 Sep 1;142:56-62. doi: 10.1016/j.drugalcdep.2014.05.023. Epub 2014 Jun 11. Pubmed PMID:24962325
7. Wetherill L, Kapoor M, Agrawal A, Bucholz K, Koller D, Bertelsen SE, Le N, Wang JC, Almasy L, Hesselbrock V, Kramer J, Nurnberger JI Jr, Schuckit M, Tischfield JA, Xuei X, Porjesz B, Edenberg HJ, Goate AM, Foroud T. Family-based association analysis of alcohol dependence criteria and severity. Alcohol Clin Exp Res. 2014 Feb;38(2):354-66. doi: 10.1111/acer.12251. Epub 2013 Sep 9. Pubmed PMID:24015780
8. Wang JC, Foroud T, Hinrichs AL, Le NX, Bertelsen S, Budde JP, Harari O, Koller DL, Wetherill L, Agrawal A, Almasy L, Brooks AI, Bucholz K, Dick D, Hesselbrock V, Johnson EO, Kang S, Kapoor M, Kramer J, Kuperman S, Madden PA, Manz N, Martin NG, McClintick JN, Montgomery GW, Nurnberger JI Jr, Rangaswamy M, Rice J, Schuckit M, Tischfield JA, Whitfield JB, Xuei X, Porjesz B, Heath AC, Edenberg HJ, Bierut LJ, Goate AM. A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53. Mol Psychiatry. 2013 Nov;18(11):1218-24. doi: 10.1038/mp.2012.143. Epub 2012 Oct 23. Pubmed PMID:23089632
9. Wang JC, Spiegel N, Bertelsen S, Le N, McKenna N, Budde JP, Harari O, Kapoor M, Brooks A, Hancock D, Tischfield J, Foroud T, Bierut LJ, Steinbach JH, Edenberg HJ, Traynor BJ, Goate AM. Cis-regulatory variants affect CHRNA5 mRNA expression in populations of African and European ancestry. PLoS One. 2013 Nov 26;8(11):e80204. doi: 10.1371/journal.pone.0080204. eCollection 2013. Pubmed PMID:24303001
10. Kapoor M, Wang JC, Wetherill L, Le N, Bertelsen S, Hinrichs AL, Budde J, Agrawal A, Bucholz K, Dick D, Harari O, Hesselbrock V, Kramer J, Nurnberger JI Jr, Rice J, Saccone N, Schuckit M, Tischfield J, Porjesz B, Edenberg HJ, Bierut L, Foroud T, Goate A. A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks. Hum Genet. 2013 Oct;132(10):1141-51. doi: 10.1007/s00439-013-1318-z. Epub 2013 Jun 7. Pubmed PMID:23743675

Abstract, Posters, Oral Presentations

1. Le N, Cregger M, Lynn N, Loret de Mola JR, Ghareeb A, Groesch K, Wilson T, Paula Diaz-Sylvester P, Braundmeier-Fleming A. (2019). Alteration of Microbial Communities and Immune Populations in Patients with Endometriosis. The American Society for Reproductive Immunology. Grand Rapid, MI. (oral)
2. Le N, Cregger M, Lynn N, Loret de Mola JR, Bremer P, Ghareeb A, Groesch K, Wilson T, Paula Diaz-Sylvester P, Braundmeier-Fleming A. (2019) Pre- and Postoperative changes in Urinary Estrogen Metabolites in Women with Endometriosis. Illinois Symposium for Reproductive Sciences. Chicago, IL. (oral)​
3. Idusuyi B, Le N, Thompson T, Gong J, Groesch K, Loret de Mola JR, Braundmeier-Fleming A. (2019). Maternal Inflammation and Urogenital Microbial Profiling as Predictors of Preterm Birth. ACOG. Nashville, TN.
4. Portugal A, Le N, Thompson T*, Gong J, Groesch K, Loret de Mola JR, Braundmeier-Fleming A. (2019). Association of Fecal Microbial Profiles and Estrogen Metabolism in Patients with Preterm Birth. ACOG. Nashville, TN.
5. Onyewuenyi T, Le N, Addo J, Groesch K, Loret de Mola JR, Braundmeier-Fleming A. (2019). Chronic peripheral inflammation and perinatal depression in high risk pregnancies. ACOG. Nashville, TN.
6. Ghareeb A, Gibson K, Maxheimer K, Cregger M, Close D, Karr M, Badger T, Le N, Groesch K, Diaz-Sylvester P, Wilson T, Brard L, Braundmeier-Fleming A. (2019). Understanding and Diagnosing endometrial cancer using multi-organ microbial taxonomic signatures. Society for Gynecological Oncology. Honolulu, HI.
7. Gibson K, Ghareeb A, Maxheimer K, Cregger M, Close D, Karr M, Badger T, Le N, Groesch K, Diaz-Sylvester P, Wilson T, Brard L, Braundmeier-Fleming A. (2018). Understanding and Diagnosing endometrial cancer using multi-organ microbial taxonomic signatures. Illinois Symposium for Reproductive Sciences. Carbondale, IL.
8. Acheampong N, Le N, Nicholson K, Idusuyi B, Thompson T, Portugal A, Ghareeb A, Groesch K, Diaz-Sylvester P, Wilson T, Gilber J, Yee A, Loret de Mola JR, Braundmeier-Fleming A. (2018). The Impact of Maternal Inflammation on Preterm Birth. Illinois Symposium for Reproductive Sciences. Carbondale, IL.
9. Le N, Cregger M, Nguyen L, Loret de Mola JR, Groesch K, Wilson T, Diaz-Sylvester P, Braundmeier-Fleming A. (2018). Alteration of microbial communities and immune populations in patients with endometriosis. Illinois Symposium for Reproductive Sciences. Carbondale, IL. (poster)
10. Kendall K, Diaz-Sylvester P, Wilson T, Groesch K, Maxheimer K, Hamilton K, Badger T, Le N, Semaan A, Braundmeier-Fleming A, Brard L. (2018). Potential Biomarkers for Endometrial Cancer. 28^th Annual Trainee Research Symposium. SIUSOM, Springfield IL.
11. Maxheimer K, Cregger M, Close D, Karr M, Badger T, Le N, Groesch K, Diaz-Sylvester P, Wilson T, Brard L, Braundmeier-Fleming A. (2018). Understanding and Diagnosing Endometrial Cancer Using Multi-Organ Microbial Taxonomic Signatures. 28^th Annual Trainee Research Symposium. SIUSOM, Springfield IL.
12. Le N, Cregger M, Nguyen L, Loret de Mola JR, Groesch K, Wilson T, Diaz-Sylvester P, Braundmeier-Fleming A. (2018). Alteration of Microbial Communities and Immune Populations in Patients with Endometriosis. Society for the Study of Reproduction. New Orleans, LA. (oral and poster)
13. Loret de Mola JR, Le N, Nguyen L, Diaz-Sylvester P, Wilson T, Groesch K, Braundmeier-Fleming A. (2018). Detection of Urinary Estrogen Metabolites in Women with Endometriosis. European Congress on Endometriosis. Vienna, Austria.
14. Le N, Roy S, Diaz-Sylvester P, Wilson T, Groesch K, Braundmeier-Fleming A. (2017). The impact of maternal inflammation on preterm birth. Society for the Study of Reproduction. Washington D.C (poster)

Assistant Professor, Department of Clinical and Administrative Sciences – (Adjunct/Part-time)
Bio:
Dr. Kim has practiced as an inpatient pharmacist at Fountain Valley Regional Hospital in Fountain Valley, CA. Later, she joined the faculty at AUHS in the Department of Clinical and Administrative Sciences. She practices as an inpatient clinical pharmacist with an acute care focus, specializing in pharmacokinetics, nutrition, emergency medicine, and antibiotic stewardship. She also serves as a preceptor for pharmacy IPPE and APPE students.

Education
PharmD – Loma Linda University, CA
PGY1, Fountain Valley Regional Hospital, CA
BS (Biochemistry Cell-Bio and Psychology) – University of California, San Diego, CA

Areas of Expertise
Acute care including PK, TPN, ID, emergency medicine

Courses Taught:
Integrated Pharmacotherapy I: Fluid, Electrolytes & Hematology
Integrated Pharmacotherapy IV: Gastroenterology and Endocrinology with Lab
Integrated Pharmacotherapy VI: Infectious Disease with Lab

Scholarship Interests:
Infectious Disease

Presentations:
Kim S, Ty P. Evaluating the Effects of CMS Sepsis Core Measure Implementation in a Community Hospital, ID Week 2020

Self-Care and Mental Health, City Council Meeting Student Presentations, 2020 (Co-Curricular Advisor)

Influenza Vaccination, City Council Meeting Student Presentations, 2020 (Co-Curricular Advisor)

Associate Professor, Department of Clinical and Administrative Sciences – (Adjunct/Part-time)
Education

Dr. Meyer received his BS and PharmD degrees from the University of the Pacific College of the Pacific and School of Pharmacy respectively.
Bio

Dr. Meyer currently serves as Associate Professor in the Clinical and Administrative Department at the American University of Health Sciences School of Pharmacy. Dr. Meyer comes to AUHS with a background of more than 40 years of pharmacy practice experience, specializing in long term care and geriatrics. His experience includes clinical practice as a consultant pharmacist, long term care pharmacy operations and administration in both long term care pharmacy companies and long term care companies providing skilled nursing and residential services.
Dr. Meyer has been active in several pharmacy organizations for many years. He has been a member of the American Society of Consultant pharmacists since 1985 and served on numerous Committees, the Board of Directors and as President and Chairman of the Board. As a long-time member of the California Pharmacists Association, Dr. Meyer has served on multiple committees, is a member for the Academy of Long Term Care and has served on the Board of Trustees. Dr. Meyer has also worked with the Pharmacy Quality Alliance on measurable criteria for pharmacists’ quality measures, and with NCPDP Workgroup 14 on electronic data standards for prescribing in nursing facilities. He is a member of the Medication Safety Officers Society and has been a member of the American Geriatrics Society, California Association for Long Term Care Medicine. He is currently a member of the Dean’s Advisory Council for Marshall B. Ketchum School of Pharmacy, and for Chapman University School of Pharmacy until 2020.
Dr. Meyer currently serves as preceptor for an IPPE and APPE practice site involved in projects relating to the role of the pharmacist in transitions of care and medication safety.

Assistant Professor, Clinical and Administrative Sciences

Education
Pharm.D – Western University of Health Sciences, Pomona, CA 2004
PGY-1 Tripler Medical Center, Honolulu, Hawaii 2005
B.S Human Physiology – University of Los Angeles, CA 2000.

Bio
Dr. Chung’s primary experience is hospital health system for nearly 20 years. Prior to becoming a pharmacist, she worked as an LVN in Long Term Care facility and Home Health Care. Fascinated with medicine, she went back to school. She graduated from UCLA with B.S. in Human Physiology, earned her Pharm.D. at Western University of Health Sciences, completed ASHP accredited PGY-1 Pharmacy Practice at Tripler Medical Center, Honolulu, HI. She had served the country as a Captain in the U.S Army at Fort Leonard Woods Community Hospital in Missouri. Dr. Chung is board certified in Pharmacotherapeutics. Her experiences include hospital pharmacy protocol clinical consultations, non-formulary medication review, antibiotic stewardship, IV preparation of compounded sterile preparations (CSPs) , USP 797, retail pharmacy, remote pharmacy order verification, prior authorization for Pharmacy Benefits Management for insurance company (Prescription Solutions). Dr. Chung is compassionate about teaching and sharing her experiences with students.

Area on interest
Acute care hospital pharmacy with a focus on Pharmacokinetics, Antibiotics Stewardship, TPN, Anticoagulation, and Critical Care.

Associate Professor of Clinical and Administrative Sciences
Education:
Doctor of Pharmacy University of the Pacific, Thomas J Long School of Pharmacy, Stockton, CA
PGY-1 Pharmacy Practice Residency – St. Joseph’s Medical Center, Stockton, CA Bachelor of Science Rutgers College, Rutgers University, New Brunswick NJ

Bio:
An experienced Clinical Manager with over 25 years in practice with pharmacy management, acute care practice, and oncology care management. Prior to joining AUHS, Dr Brady leads clinical programs and productivity at a large community district hospital in Monterey County managing all clinical program development, education, training, and implementation, chairing Pharmacy and Therapeutics, Glycemic, Antimicrobial Stewardship and Medication Safety Committees. She directs and oversees all aspects of medication policy and protocol development, regulatory and best practices standards in Oncology Infusion Center and hospital operations including 340B program standards.

Dr. Brady is actively involved in mentoring and training Pharmacy students in institutional and internal medication rotations and serves as Pharmacy Technician program instructor.

Areas of expertise:
Acute care including Code Blue, Code Stroke, PK, TPN, Infectious Disease, Oncology

Presentations:
Implementation of an Antimicrobial Stewardship Program ASP managed by an Infectious Disease Physician and Pharmacists in a Community Hospital, ASHP Midyear 2019, Las Vegas, NV

Position: Assistant Professor of Clinical and Administrative Sciences (Adjunct/ Part-time)
Education:
Doctor of Pharmacy from Western University of Health Sciences
Bachelor of Science in Biochemistry from California State University, Fullerton
Biography:
Dr. Garcia graduated with his PharmD from Western University of Health Sciences. From there, he worked as an outpatient pharmacist for Safeway where he would counsel patients and give vaccinations. He then moved to Apple Valley where he worked as an inpatient pharmacist for St. Mary Medical Center. While working there, he also became a staff pharmacist for Telnet-Rx Telepharmacy where he would help with remote order entry. There he learned many electronic health record software programs and verified medications throughout different hospital systems in California. Now, he works at St. Francis Medical Center where he monitors and doses clinically significant medications such as vancomycin, heparin, aminoglycosides and epoetin.
Invention:
While Dr. Garcia was studying at Western University of Health Sciences, he created an invention for extracting liquid from capsules which is still in use in UCI Medical Center. This invention is useful for medications like nimodipine which is used for stroke patients. His invention is published on the UCI Beall Applied Innovation website and patented by UCI. He was featured on Western University’s magazine, RxBound, as the college’s first student published inventor. Below are the links for the invention and interview.
https://techtransfer.universityofcalifornia.edu/NCD/26018.html
https://webassets.westernu.edu/flipbooks/RxBound_2017_issue2_Exp/index.html

Jasen Chau, Pharm.D., APh.

Assistant Professor, Department of Clinical and Administrative Sciences

Biography: Dr. Jasen Chau earned a Doctor of Pharmacy degree from the University of Southern California (USC) and completed the USC School of Gerontology graduate studies program. At USC, he also completed a one-year post-graduate residency in geriatric pharmacy practice. He’s also a pharmacist with advanced practice training (APh.). Prior to joining AUHS in 2019, he worked as a clinical pharmacist in a number of Southern California hospitals. In addition, he has worked as a Director of Pharmacy in a variety of clinical settings, including hospitals, clinics, long-term acute care facilities, and independent specialty pharmacies, where he was responsible for clinical decisions, financial management, drug adherence, adverse event/error prevention, and efficient medication acquisition. In the specialty pharmacy setting, he has also managed patients with hemophilia, diabetes, cardiac complications, geriatic conditions, men’s health issues, and HIV/AIDS. Dr. Chau has also instructed students in pharmacy technician programs at other universities, preparing them to become board-certified technicians.

Education: Doctor of Pharmacy – University of Southern California (USC), Los Angeles

Geriatric Pharmacy Practice Residency PGY-1- University of Southern California (USC), Los Angeles

Bachelor of Science (Biological Sciences, with minor in Chemistry) – University of Nevada, Las Vegas (UNLV)

Areas of Expertise: Hospital Practice, Community Practice, Geriatrics

Courses Taught: Professional Communications

Pharmacy Practice – Community/Outpatient

Health Informatics & Patient Safety

Integrated Pharmacotherapy Cardiology

Integrated Pharmacotherapy Oncology & Nutrition – Lymphoma, Leukemia, Lung Cancer

Integrated Pharmacotherapy Urology and Reproductive System – Men’s health

Geriatric Pharmacotherapy & Gerontology

Introductory Pharmacy Practice Experiences – Hospital/Institution

Publication: Alamdar Hussain, PhD, Jasen Chau, PharmD, Heejung Bang, PhD, Lee Meyer, PharmD, Mohammed Islam, PhD. Readiness, Reception, and Performance of Students in a Communications Course Delivered Amid the Pandemic. American Journal of Pharmaceutical Education. July 2021.

Scholarship Interests: Pharmacy Education, Academia, & Pedagogy; Leadership in Pharmacy

Dr. Robert H. Zeiler, Professor of Pathophysiology, School of Pharmacy and Professor of Physiology, School of Medicine.

BIO
Dr. Robert H. Zeiler, Professor of Pathophysiology, School of Pharmacy and Professor of Physiology, School of Medicine, has scientific degrees from Long Island University (B.S., Biology, 1971 and M.S. Physiology, 1973) and earned his doctorate in Biology from New York University, Washington Square, 1981. Prior to entering the pharmaceutical industry, he performed original research in cardiac electrophysiology and biophysics, particularly in arrhythmia and ischemia, publishing in over 50 abstracts, presentations and peer-reviewed journals.

EDUCATION

1981
Doctor of Philosophy, Biology
New York University
Graduate School of Arts and Science
Washington Square
New York, New York, USA

1973
Master of Science, Physiology
Long Island University
Flatbush Avenue Extension
Brooklyn, New York, USA

1971
Bachelor of Science, Biology
Long Island University
Flatbush Avenue Extension
Brooklyn, New York, USA

MEMBERSHIPS

1995 to Present American Heart Association
2010 to Present Society of Quality Assurance

PUBLICATIONS AND PRESENTATIONS

1. Gelles JM and Zeiler RH: “ELECTRO-MECHANICAL COUPLING IN CARDIAC MUSCLE; EFFECTS OF CALCIUM IONOPHORES.” Circulation, 55 and 66: III-46, 1977.

2. Gelles JM and Zeiler RH: “IS NA-CA EXCHANGE IN CARDIAC PURKINJE FIBERS ELECTROGENIC?.” Fed. Proceedings, 37:3, 1987, 1978.

3. Zeiler RH, Gelles JM, and Krasnow N: “THE EFFECTS OF NATURAL AND SYNTHETIC IONOPHORES ON THE ACTION POTENTIAL AND ISOMETRIC CONTRACTION OF CARDIAC PURKINJE FIBERS.” Fed. Proceedings, 37.3, 1898, 1978.

4. Gelles JM, Zeiler RH, and Krasnow N: “ELECTRO-MECHANICAL COUPLING IN CARDIAC PURKINJE FIBERS: EFFECTS OF IONOPHORE X-537A.” Bull. N.Y. Aced. Med. 54-3: 316-317, 1978.

5. Gelles JM and Zeiler RH: “ELECTROGENIC HYPERPOLARIZATION IN CANINE CARDIAC PURKINJE FIBERS EXPOSED TO CALCIUM IONOPHORES.” Experientia 34:619, 1978.

6. El-Sherif N, Gomes JAC, Kelen GJ, Khan RG, Kang PS, and Zeiler RH: “ELECTRO-PHYSIOLOGIC, BIOCHEMICAL AND PHARMACOLOGICAL ASPECTS OF REENTRANT VENTRICULAR ARRHYTHMIAS IN THE LATE MYOCARDIAL INFARCTION PERIOD. “IN: “SUDDEN DEATH.”

7. El-Sherif N, Gomes JAC, Kelen GJ, Khan RG Kang PS, and Zeiler RH: “ELECTRO-PHYSIOLOGY OF REENTRANT VENTRICULAR ARRHYTHMIAS IN THE LATE MYOCARDIAL INFARCTION PERIOD.” In: “New Trends in Medical and Surgical Management of Tachyarrhythmias.” Editors, L. Seipl, H.D. Schulti. 1980.

8. El-Sherif N, Zeiler RH, Gough W: “EFFECTS OF CATECHOLAMINES, VERAPA¬MIL AND TETRODOTOXIN ON TRIGGERED AUTOMATICITY IN CANINE ISCHEMIC PURKINJE FIBERS.” Circulation 62: Suppl. III; 1076, 1980.

9. Zeiler RH, Gough WB, Sung R, El-Sherif N: “ELECTROPHYSIOLOGIC EFFECT OF PROPAFENONE IN CANINE ISCHEMIC CARDIAC CELLS.” Am. J. Cardiol, 47:483, 1981.

10. El-Sherif N, Gough, WB, Zeiler RH, Mehra R: “EPICARDIAL MAPPING OF TRIGGERED
AUTOMATICITY IN CANINE ISCHEMIC PURKINJE FIBERS.” Am. J. Cardiol., 47:489, 1981.

11. Gough WB, Zeiler RH, El-Sherif N: “THE ANTIARRHYTHMIC ACTION OF NIFEDIPINE ON TRIGGERED ACTIVITY IN ONE DAY OLD ISCHEMIC ENDOCARDIUM.” Circulation 64: Suppl. IV; 274, 1981.

12. El-Sherif N, Gough WB, Zeiler RH, Mehra R: “DIFFERENT MECHANISMS FOR SPONTANEOUS AND INDUCED VENTRICULAR RHYTHMS IN 24 HOUR-OLD MYOCARDIAL INFARCTION IN THE DOG.” Circulation 64: Suppl. IV; 218, 1981.

13. Mehra R, Zeiler RH, Gough WB, El-Sherif N: “MECHANISM OF REPETITIVE VENTRICULAR RESPONSES RVR’S BLOCK.” Circulation 64: Suppl. IV; 172, 1981.

14. Gough WB, Zeiler RH, Barreca P, El-Sherif N: “THE HYPOTENSIVE EFFECTS OF COMMERCIAL INTRAVENOUS AMIODARONE IN DOGS: DEPENDENCE ON THE DILUENT POLYSORBATE 80.” J. of Cardiovascular Pharm., 4:375-380, 1982.

15. Mehra R, Kelen GJ, Zeiler RH, Zephiran D, Fried P, Gomes JA, El-Sherif N: “NON-INVASIVE HIS BUNDLE ELECTROGRAM: VALUE OF THREE VECTOR LEAD RECORDINGS.” Am. J. Cardiol., 49:344-348, 1982.

16. El-Sherif N, Mehra R, Gough WB, Zeiler RH: “VENTRICULAR RHYTHMS IN CANINE ONE-DAY-OLD MYOCARDIAL INFARCTION. EVIDENCE FOR FOCAL AND REENTRANT MECHANISMS.” Circulation Research, 51:152-166, 1982.

17. Mehra R, Zeiler RH, Gough WB, El-Sherif N: “REENTRANT VENTRICULAR ARRHYTHMIAS IN THE LATE MYOCARDIAL INFARCTION PERIOD. 9. ELECTROPHYSIOLOGICAL ANATOMICAL CORRELATION OF REENTRANT CIRCUITS.” Circulation. 67(1):11-24, January, 1983.

18. Gough WB, Zeiler RH, El-Sherif N: “EFFECTS OF CALCIUM AND CALCIUM ANTAGONISTS ON TRIGGERED ACTIVITY IN ONE-DAY-OLD CANINE ISCHEMIC ENDOCARDIUM.” Am J. Cardiol., 49:914, 1982.

19. El-Sherif N, Mehra R, Gough WB, Zeiler RH: “MECHANISM OF REENTRANT RHYTHMS INDUCED BY BURSTS OF RAPID VENTRICULAR STIMULATION IN THE ISCHEMIC CANINE HEART.” Am J. Cardiol., 49:934, 1982.

20. Zeiler RH, Strand FL, El-Sherif N: “CANINE LEFT ATRIAL TISSUE SPECIFICALLY BINDS ADRENOCORTICOTROPIC HORMONE.” Am. J. Cardiol., 49:1037, 1982.

21. Zeiler RH, Strand FL, El-Sherif N: “ELECTROPHYSIOLOGICAL AND CONTRAC¬TILE RESPONSES OF CANINE ATRIAL TISSUE TO ADRENOCORTI¬COTRO¬PIN.” Peptides, 3:815, 1982.

22. Zeiler RH, Gough WB, El-Sherif N: “ROLE OF CA2+ AND NA2+ ON AFTER DEPOLARIZATIONS IN CANINE ISCHEMIC PURKINJE FIBERS.” Circulation, 66:II-78, 1982.

23. Gough WB, Zeiler RH, El-Sherif N: “BASIS FOR REDUCED TRANSMEMBRANE POTENTIALS ASSORTED WITH TRIGGERED ACTIVITY IN ISCH¬EMIC SUBENDOCARDIAL PURKINJE FIBERS.” Circulation, 66:II-156, 1982.

24. Hariman RJ, Zeiler RH, Gough WB, El-Sherif N: “THE EFFECT OF OUABAIN ON TRIGGERED ACTIVITY IN ONE DAY ONE CANINE INFARCTION.: Circulation, 66:II, 1982.

25. El-Sherif N, Gough WB, Zeiler RH, Mehra R: “VENTRICULAR RHYTHMS IN ONE-DAY-OLD CANINE INFARCTION ARE DUE TO TRIGGERED ACTIVITY.” Circulation, 66:II-357, 1982.

26. El-Sherif N, Mehra R, Gough WB, Zeiler RH: “TERMINATION OF REENTRANT CIRCUITS IN CANINE INFARCTION BY CRYOTHERMAL TECH¬NIQUES.” Circulation, 66:II-358, 1982.

27. El-Sherif N, Mehra R, Gough WB, Zeiler RH: “VENTRICULAR ACTIVATION PATTERNS OF SPONTANEOUS AND INDUCED VENTRICULAR RHYTHMS IN CANINE ONE-DAY-OLD MYOCARDIAL INFARCTION.” Circulation Research, 51:152-166, 1982.

28. El-Sherif N, Mehra R, Gough WB, Zeiler RH: “VENTRICULAR ACTIVATION PATTERNS OF PLEOMORPHIC VENTRICULAR TACHYCARDIAS THAT TERMINATE SPONTANEOUSLY OR DEGENERATE INTO VENTRICULAR FIBRILLATION.” J. American College of Cardiology, 2:621, 1983.

29. Gough WB, Zeiler RH, El-Sherif N: “EFFECTS OF DILTIAZEM ON TRIGGERED ACTIVITY IN ONE-DAY-OLD ISCHEMIC ENDOCARDIUM OF THE DOG.” J. American College of Cardiology, 2:692, 1983.

30. Mehra E, Zeiler RH, Gough WB, El-Sherif N: “REENTRANT VENTRICULAR ARRHYTHMIAS CORRELATION OF REENTRANT CIRCUITS. THE ANATOM¬ICAL BASIS FOR REENTRY.” Circulation 67(1):11-24, 1983.
31. El-Sherif N, Mehra R, Gough WB, Zeiler RH: “EFFECTS OF REVERSIBLE COOLING ON REENTRANT TACHYCARDIA IN CANINE INFARCTION.” Pace, 6:5, 1983.

32. El-Sherif N, Gough WB, Zeiler RH, Mehra R: “TRIGGERED RHYTHMS IN ONE-DAY-OLD MYOCARDIAL INFARCTION IN THE DOG.” Circulation Research, 52:566-579, 1983.

33. El-Sherif N, Mehra R, Gough WB, Zeiler RH: “REENTRANT VENTRICULAR ARRHYTHMIAS IN THE LATE MYOCARDIAL INFARCTION PERIOD AND INTERRUPTION OF REENTRANT CIRCUITS BY CRYOTHERMAL TECHNIQUES.” Circulation, 63:644-656, 1983.

34. El-Sherif N, Mehra R, Gough WB, Zeiler RH: “EFFECTS OF REVERSIBLE COOLING ON REENTRANT TACHYCARDIAS IN CANINE INFARCTION.” Physiologist 26:A91, 1983.

35. Gough WB, Zeiler RH, El-Sherif N: “EFFECTS OF CAFFEINE ON TRIGGERED ACTIVITY IN ONE-DAY-OLD ISCHEMIC ENDOCARDIUM OF THE DOG.” Circulation 68:III-20, 1983.

36. El-Sherif N, Mehra R, Gough WB, Zeiler RH: “BURST PACING VERSUS PREMATURE STIMULATION IN THE INDUCTION OF REENTRY.” J. Amer. Coll. Cardiol. 3:587, 1984.

37. Mehra R, Gough WB, Zeiler RH, El-Sherif N: “MECHANISM OF LIDOCAINE ACTION ON REENTRANT VENTRICULAR RHYTHMS IN THE CANINE ISCHEMIC HEART.” J. Amer. Coll. Cardiol. 3:542, 1984.

38. Gough WB, Zeiler RH, El-Sherif N: “EFFECTS OF NIFEDIPINE ON TRIGGERED ACTIVITY IN ONE-DAY-OLD MYOCARDIAL INFARCTION IN DOGS.” Amer. J. Cardiol. 53:303-306, 1984.

39. Mehra R, Gough WB, Zeiler RH, El-Sherif N: “DUAL VENTRICULAR STIMULA¬TION FOR PREVENTION OF REENTRANT VENTRICULAR ARRHYTH¬MIAS.” J. Amer. Coll. Cardiol. 3:472, 1984.

40. Gough WB, Zeiler RH, El-Sherif N: “DEPENDENCE OF TRIGGERED ACTIVITY ON DIASTOLIC POTENTIALS IN ONE-DAY-OLD ISCHEMIC PURKINJE FIBERS.” J. Amer. Coll. Cardiol. 3:477, 1984.

41. El-Sherif N, Gough WB, Zeiler RH: “THE EFFECT OF DIFFERENTIAL SHORTENING OF REFRACTORINESS IN SUCCESSIVE SHORT CARDIAC CYCLES ON THE INITIATION AND TERMINATION OF REENTRY IN THE ISCHEMIC CANINE HEART.” J. Amer. Coll. Cardiol. 3:477, 1984.

42. Zeiler RH, Gough WB, El-Sherif N: “ELECTROPHYSIOLOGIC EFFECT OF PROPAFENONE ON CANINE ISCHEMIC CARDIAC CELLS.” Amer. J. Cardiol. 54:424-429, 1984.

43. El-Sherif N, Mehra R, Gough WB, Zeiler RH: “REENTRANT VENTRICULAR ARRHYTHMIAS IN THE LATE MYOCARDIAL INFARCTION PERIOD: II. BURST PACING VERSUS MULTIPLE PREMATURE STIMULATION IN THE INDUCTION OF REENTRY.” J. Amer. Coll. Cardiol. 4:295-304, 1984.

44. Zeiler RH, Tobiasz C, Henkin R, Gough WB, El-Sherif N: “THE EFFECTS OF ISCHEMIA ON INTRACELLULAR POTASSIUM ACTIVITY AND MEMBRANE POTENTIAL IN CANINE ENDOCARDIAL TISSUE.” Circulation, 70(4): 898, 1984.

45. Gough WB, Zeiler RH, El-Sherif N: “EFFECTS OF DILTIAZEM ON TRIGGERED ACTIVITY IN CANINE ONE-DAY-OLD INFARCTION. Cardiovasc Res 18:339-343, 1984.

46. El-Sherif N, Gough WB, Hariman R, Zeiler RH: “MECHANISMS OF TERMINATION OF ACCELERATION OF REENTRANT TACHYCARDIA BY BURST PACING.” Circulation, 70:II-91, 1984.

47. Hariman RH, Zeiler RH, Gough WB, El-Sherif N: “ENHANCEMENT OF TRIGGERED ACTIVITY IN ISCHEMIC PURKINJE FIBERS BY OUABAIN. A MECHANISM OF INCREASED SUSCEPTIBILITY TO DIGITALIS TOXICITY IN MYOCARDIAL INFARCTION.” J. Amer. Coll. Card. 5(3):672-679, 1985.

48. El-Sherif N, Gough WB, Hariman R, Zeiler RH: “ROLE OF NON UNIFORM REFRACTORY DISTRIBUTION VERSUS ANISOTROPIC ANATOMIC PROPERTIES IN THE INITIATION OF REENTRANT EXCITATION IN THE CANINE POST-INFARCTION HEART.” J. Amer. Coll. Card. 5:390, 1985.

49. El-Sherif N, Gough WB, Zeiler RH, and Hariman R: “REENTRANT VENTRICULAR ARRHYTHMIAS IN THE LATE MYOCARDIAL INFARCTION PERIOD. 12. SPONTANEOUS VERSUS INDUCED REENTRY AND INTRA¬MURAL VERSUS EPICARDIAL CIRCUITS. J. Am. Coll. Cardiol. 6(1):124-132, 1985.

50. Gough WB, Mehra R, Restive M, Zeiler RH and El-Sherif N: “REENTRANT VENTRICULAR ARRHYTHMIAS IN THE LATE MYOCARDIAL INFARCTION PERIOD IN DOG. 13. CORRELATION OF ACTIVATION AND REFRACTORY MAPS.” Circ. Res. 57(3):432-442, 1985.

51. El-Sherif N, Gough WB, Zeiler RH, Craelius W, and Restivo M: “ROLE OF NON UNIFORM REFRACTORY DISTRIBUTION VERSUS ANISOTROPIC PROPERTIES IN THE INITIATION OF REENTRANT EXCITATION IN THE CANINE POST INFARCTION HEART.” J. Amer. Coll. Cardiol. 5(2):390, 1985.

52. Fontaine JM, Zeiler RH, Henkin R, El-Sherif N: “SIMULTANEOUS MONOPHASIC ACTION POTENTIAL RECORDING AND REGIONAL ENDOCARDIAL REFRACTORY PERIOD DETERMINATION USING A NEW DUAL PUR¬POSE CONTACT ELECTRODE CATHETER., PACE 9(2):278, 1986.

53. Craelius W, Chen V, El-Sherif N, and Zeiler RH: “IN VIVO RECORDING OF EARLY AFTER DEPOLARIZATION PRECEDING TORSADES DE POINTES.” J. Amer. Coll. Cardiol. 7:124A, 1986.

54. Kelen GJ, Henkin R, Restivo M, Zeiler RH, Caref EB, and El-Sherif N: “SIGNAL AVERAGING OF HIGH GAIN HOLTER ECG RECORDINGS VALIDATION OF A NEW TECHNIQUE FOR DETECTION OF AFTER POTENTIALS.” J. Amer. Coll. Cardiol. 7:104A, 1986.

55. Zeiler RH, Sequeira JM, Henkin R, Sedlis SP, El-Sherif N: “LYSOPHOSPHATIDYL CHOLINE: PROBABLE AGENT FOR MAINTAINED TRIGGERED ACTIVITY IN ISCHEMIC CARDIAC PURKINJE FIBERS.” J. Amer. Coll. Cardiol. 9:252, 1987.

56. El-Sherif N, Zeiler RH, Craelius W, Henkin R, Gough WB: “BRADYCARDIA-DEPENDENT QTU PROLONGATION AND TORSADES-DE-POINTES DUE TO EARLY AFTER-DEPOLARIZATIONS.” Circulation 76:429, 1987.

57. El-Sherif N, Zeiler RH, Craelius W, Gough WB, Henkin R: “2:1 BLOCK OF AN EARLY AFTER-DEPOLARIZATION AS A MECHANISM FOR TB ALTERNANS.” J. Amer. Coll. Cardiol. 11:254A, 1988.

58. El-Sherif N, Zeiler RH, Craelius W, Gough WB, Henkin R. QTU PROLONGATION AND POLYMORPHIC VENTRICULAR TACHYARRHYTHMIAS DUE TO BRADYCARDIA DEPENDENT EARLY AFTERDEPOLARIZATIONS. Circ Res. 1988; 63:286-305.

Pantelina Zourna Hargaden, MD, MPH, PhD currently serves as an Assistant Professor of Public Health and Epidemiology in the AUHS School of Pharmacy.
Dr. Zourna Hargaden is an experienced epidemiologist and physician in Internal Medicine, with more than 15 years of experience in the US and Europe. Prior to joining AUHS, she has worked in epidemiological research for NIH projects through Athens University/Harvard University as well as in European Prospective Investigation into Cancer and Nutrition (EPIC) studies. She has worked in breast cancer research, as part of the team of internationally known Professor Dimitrios Trichopoulos (Vincent L. Gregory Professor of Cancer Prevention and Professor of Epidemiology at Harvard Chan School of Public Health), who was also the academic advisor of her doctoral thesis.
As a graduate of the MPH program at Harvard Chan School of Public Health and a public health practitioner, she investigated the risk factors of breast cancer and worked to raise awareness of cancer. She has extensive experience optimizing study designs and statistical analysis for interdisciplinary projects. Her scientific work has been published in peer-reviewed medical journals (e.g. Annals of Internal Medicine, BMJ, etc.)
As a physician in Internal Medicine, Dr. Zourna Hargaden worked with ethos, with underserved populations in Greece, pioneered efforts to improve patient safety and performance, reduce preventable rehospitalizations and improve access of underserved populations to primary, secondary, and tertiary care. During her practice, she supervised multiple medical students and mentored international graduate students in public health, as an ambassador for Harvard Chan School of Public Health. She is enthusiastic about health sciences education, with a public health focus, to meet the current needs of healthcare in our country.
She is a member of the American Public Health Association (APHA), the International Agency for Research on Cancer (IARC), and the American Society for Clinical Oncology (ASCO).

Jonathan Sheng, PhD
Assistant Professor of Pharmaceutical Sciences (Adjunct/Part-time Faculty)

Education
Post-Ph. D. Pharmaceutical Sciences/Medicinal Chemistry
Division of Medicinal and Natural Products Chemistry
College of Pharmacy, University of Iowa, Iowa City, Iowa
Ph. D. Toxicology/Drug Metabolism
Department of Environmental Health Sciences and Toxicology
School of Public Health, State University of New York, Albany, New York
B. M. Medicine
Kunming Medical University, Kunming, China

Bio
Dr. Jonathan Sheng received his Ph.D. training in Environmental Sciences and Toxicology at State University of New York at Albany and his post-doctoral training in Medicinal Chemistry/Pharmaceutical Sciences at the University of Iowa. He currently is a regular member of American Chemical Society (ACS), American Association of Pharmaceutical Scientists (AAPS), American Society for Pharmacology and Experimental Therapeutics (ASPET), and International Society for the Study of Xenobiotics (ISSX).

Dr. Sheng’s research interests and expertise are in the areas of drug and xenobiotic metabolism, drug analysis (both small molecules and biological molecules), enzymology (P450s and cytosolic sulfotransferases), protein chemistry (protein structure/function, molecular mobility, subcellular localization, and stereochemistry), transgenic animal model development, and drug/environmental chemical-protein interaction studies.

Publications
S heng, J.J, Wang, Y, Turesky, R.J., Kluetzman K, Zhang Q.Y., Ding X. (2016) Novel Transgenic Mouse Model for Studying Human Serum Albumin as a Biomarker of Carcinogenic Exposure. Chemical Research in Toxicology 29:797-809
S heng, J.J. and Acquaah-Mensah, G.K. (2011) Subcellular location and molecular mobility of human sulfotransferase SULT1C1 in living human embryonic kidney 293 cells. Drug Metabolism and Disposition 36:1-4.
Kapoor, R. and S heng, J.J. (2008) Transfection of human CA-HPV-10 cells with sulfotransferase SULT1E1 affects estrogen signaling and gene expression. Drug Metabolism and Disposition 36:316-21.
Kapoor, R., Nimmagadda, D. and Sheng, J.J. (2007) Cellular localization studies on human estrogen sulfotransferase SULT1E1 in human embryonic kidney 293 cells. Drug Metabolism and Disposition 35:17-20.
S heng, J.J., Saxena, A. and Duffel, M.W. (2004) Influence of phenylalanines 77 and 138 on the stereospecificity of aryl sulfotransferase IV. Drug Metabolism and Disposition 32:559- 565.
S heng, J.J., and Duffel, M.W. (2003) Enantioselectivity of human hydroxysteroid (alcohol) sulfotransferase ST2A3 (SULT2A1) for 1-naphthyl-1-ethanol, a model 1-arylethanol. Drug Metabolism and Disposition 31:697-700.
Shibutani, , Ravindernath, A., Terashima, I., Suzuki, N., Laxmi, Y.R.S., Kanno, Y., Suzuki, M., Apak, T.I., S heng, J.J., and Duffel, M.W. (2001) Mechanism of lower genotoxicity of toremifene compared with tamoxifen. Cancer Research 61:3925-3931.
S heng, J.J., Sharma, V, and Duffel, M.W. (2001) Measurement of aryl and alcohol sulfotransferase activity. Current Protocols in Toxicology 1:4.5.1-4.5.9. John Wiley & Sons, Inc., New
S heng, J.J., and Duffel, M.W. (2001) Bacterial expression, purification, and characterization of rat hydroxysteroid sulfotransferase STa.Protein Expression and Purification 21:235-242.
S heng, , Hua, Z., Guo, J., Cagganna, M., and Ding, X. (2001) Identification of a new human CYP2A gene fragment with close linkage to CYP2GP1. Drug Metabolism and Disposition 29:4-7.
S heng, J.,Guo, J., Hua, Z., Cagganna, M., and Ding, X. (2000) Characterization of human CYP2G genes: widespread loss-of-functional mutations and genetic polymorphism. Pharmacogenetics 10:667-678.
Su, , Sheng, J.,Lipinskas, T.W., and Ding, X. (1996) Expression of P450 2A genes in rodent and human olfactory mucosa. Drug Metabolism and Disposition 24:884-890.
S heng, J., and Ding, X. (1995) Identification of human genes related to olfactory-specific CYP2G1. Biophy. Res. Com. 218:570-574.
Ding, X., Spink, D.C., Bhama, J.K., Sheng, J., Vaz, N.D., and Coon, M. J. (1995) Metabolic activation of a potent olfactory-specific toxicant, 2,6-dichlorobenzonitrile (DCBN), an olfactory-Specific toxicant, by rat, rabbit, and human cytochrome P450: role of 2A and 2E isoforms. Pharmacology 49:1113-1121.
Kittel, M., S heng, J., Sellinger, O., and Domino, E.F. (1994) Effects of MK-801 and PCP on rat brain cortical respiratory metabolism. Pharmacology Communications 4:258-261.
Domino, E.F., Yao, L.K., Sheng, J., Grekin, R.J., and Malvin, R.L. (1993) Is nitric oxide involved in mediating rat open field behavior? Pharmacology Communications 3:175-178.
Domino, E.F., and Sheng, J. (1993) N-methyl-D-aspartate receptor antagonist and dopamine D1 and D2 agonist interactions in 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine induced hemiparkinsonian monkeys. Pharmacol. Exp. Ther. 264:221-225.
Domino, E.F., and Sheng, J. (1993) Relative potency and efficacy of some dopamine agonists with varying selectivities for D1 and D2 receptors in MPTP-induced hemiparkinsonian monkeys. Pharmacol. Exp. Ther.265:1387-1391.
El Karib, A.O., Sheng, J., Betz, A.L., and Malvin, R.L. (1993) The central effects of a nitric oxide synthase inhibitor (N-nitro-L-arginine) in blood pressure and plasma renin. Exper. Hypertension 15:819-822.
ABSTRACTS AT NATIONAL AND INTERNATIONAL MEETINGS
Lu, S., Li, L., S heng, J., Spink, D. and Aldous, K. Comparison of Untargeted Methods using GC-MS and LC-TOF-MS/MS for Analysis of K2/Spice Synthetic Cannabinoids in Herbal 2017 US MSACL (The Association for Mass Spectrometry Applications to the Clinical Lab), Palm Springs, CA.
Ding , S heng, J.J, Wang, Y, Kluetzman K, Zhang Q.Y., and Turesky, R.J. (2016) Transgenic Mouse Development for Studying Human Serum Albumin as a Biomarker of Carcinogenic Exposure. Experimental Biology 2016/ American Society for Pharmacology and Experimental Therapeutics, San Diego, CA.
Paul, P. Suwan, J. Sheng, J.J.Linhardt, R.J. Dordick, J. Liu, J. (2012) Assays for enzymes used in the chemoenzymatic synthesis of heparin American Chemistry Society 243rd National Meeting, Philadelphia,
Paul, P. Suwan, J. Sheng, J.J.Linhardt, R.J. Dordick, J. Liu, J. (2012) Assays for enzymes used in the chemoenzymatic synthesis of heparin American Institute of Chemical Engineers (AIChE) Annual Meeting 2012, Pittsburgh,
Kapoor, and S heng, J. (2008) Studies on the regulatory roles of human estrogen sulfotransferase SULT1E1 in the expression of signal transduction-related genes in human prostate cancer CA-HPV-10 cells. Experimental Biology 2008/American Society for Pharmacology and Experimental Therapeutics, San Diego, CA.
Kapoor, and Sheng, J. (2007) DNA microarray analysis suggests a regulatory role of human estrogen sulfotransferase SULT1E1 in the expression of signal transduction-related genes in human prostate cancer CA-HPV-10 cells. Experimental Biology 2007/ American Society for Pharmacology and Experimental Therapeutics, Washington DC.
Nimmagadda, D. and Sheng, J. (2007) Immunochemical characterization of human sulfotransferase SULT1E1 in HEK293 cells. Poster presented at Experimental Biology 2006/ American Society for Pharmacology and Experimental Therapeutics, San Francisco,
Nimmagadda, D., Greiff, A., Gustad, T., and Sheng, J.J. (2005) Overexpression of hydroxysteroid sulfotransferase SULT2A1 enhances the cytotoxicity of N-hydroxy-2- acetylaminofluorene in human embryonic kidney 293 cells. Poster presented at Experimental Biology 2005/American Society for Pharmacology and Experimental Therapeutics, San Diego, CA.
Greiff, H. and Sheng, J.J. (2004) Quantitative analysis of gene expression of hydroxysteroid/ alcohol sulfotransferase (SULT2A1) and estrogen sulfotransferase (SULT1E1) in normal and malignant human prostate cell lines.Poster presentation at Experimental Biology 2004/ American Society for Pharmacology and Experimental Therapeutics, Washington, DC.
S heng, J. J., and Duffel, M. W. (2002) Enantioselectivity of human hydroxysteroid (alcohol) sulfotransferase ST2A3 for 1-naphthyl-1-ethanol, a model 1-arylethanol. 16th World Congress of Pharmacology, San Francisco,
S heng, J. J., Saxena, A., Sharma, V., and Duffel, M. W. (2002) Studies on the molecular basis for the stereoselectivity of rat aryl sulfotransferase IV (ST1A1). Poster presentation at Experimental Biology 2002 /American Society for Pharmacology and Experimental Therapeutics, New Orleans,
S heng, J. J., and Duffel, M. W. (2001) Expression, rapid purification, and stereoselectivity of recombinant hydroxysteroid sulfotransferase STa (ST2A2). 10th International Society for the Studies of Xenobiotics (ISSX) North American Meeting, Indianapolis,
S heng, J., Hua, Z, and Ding, X. (1997) Cloning and characterization of a human nasal cDNA related to olfactory-specific CYP2G1. 36th Society of Toxicology Annual Meeting, Cincinnati, OH.
Ding, X., Spink, D. C., Bhama, J. K., Sheng, J., Vaz, N. D., and Coon, M. J. (1995) Metabolic activation of a potent olfactory-specific toxicant, 2,6-dichlorobenzonitrile (DCBN), an olfactory-Specific toxicant, by rat, rabbit, and human cytochrome P450: role of 2A and 2E Experimental Biology 1995/American Society for Biochemistry and Molecular Biology, Washington, DC.

Position: Full Professor of Clinical and Administrative Sciences (Adjunct/Part-time)

Biography:
Board Certified Hematologist-Oncologist with over 46 years of experience in hematology, medical oncology, and internal medicine. Dr. Overby’s clinical experiences and expertise over 46 years included leadership positions, academic appointments, and professional presentations in varied health care organizations. In his leadership role, he held a two-term Chief of Staff at St. Francis Medical Center, Chairman of Bioethics Committee, Director of Tumor Board, President of Jason-West Society, and currently he Director of Hematology-Oncology Division, Martin Luther King Jr., Outpatient Center. Adding to his expertise and experience, Dr. Overby held positions as physician-specialist at City of Hope National Medical Center, Martin Luther King Hospital Outpatient and Urgent Care clinic. Physician-owner of Halline Overby, MD Inc., Dr. Overby was also a physician-partner with Pacific Hematology-Oncology, Inc., and holds long-term hospital appointments. A member of Memorial Care Physician Society which drives clinical outcomes and performance for Memorial Care Health System.

Education:
Doctor of Medicine (1975): Howard University College of Medicine, Washington, D.C.
Fellowships: Hematology-Oncology:
• University of California Los Angeles,
• Veterans Administration Hospital, Sepulveda, CA
• University of California, Davis
• Veterans Administration Hospital, Martinez, CA

Residencies:
Internal Medicine:
• Martin Luther King, Jr., Medical Center,
• Los Angeles, CA
Internship:
• Los Angeles County-University of Southern California
• Medical Center, Los Angeles, CA

Areas of Expertise:
Hematology – Oncology, Internal Medicine, Medical Oncology, Hematology

Professional Licensure & Certifications
Doctor of Medicine License (1975): California Board of Medicine
American Board of Internal Medicine (1976): Washington, D.C.
American Board of Medical Oncology (1983):
Academic Appointments
Assistant Professor: Charles R. Drew University of Medicine and Science, Los Angeles, CA
Hospital Appointments
Los Alamitos Medical Center, 3751 Katella Avenue,
Los Alamitos, CA 90720

Long Beach Memorial Medical Center,
2801 Atlantic Avenue, Long Beach, CA 90806

St. Francis Medical Center, 3630 E. Imperial Highway,
Lynwood, CA, 90262

Professional Societies
• Physician for a National Health Program
• National Medical Association
• American Society of Clinical Oncology
Leadership Positions
• Director, Hematology-Oncology Division, Martin Luther King Jr., Outpatient Center
• Chairman of Bioethics Committee, St. Francis Medical Center
• Director of Tumor Board, St. Francis Medical Center
• Chief of Staff, St. Francis Medical Center
• President, Jason-West Medical Society, Lynwood, CA

Professional Presentations
Monthly Tumor Board, Martin Luther King Outpatient Center /Charles Drew University
Medical Grand Rounds, “Prostate Cancer Screening”. Charles R. Drew College of Medicine and Science Speaker-Panelist: “Prevention, Treatment, and Control of Cancer In Our Community”.
California Science Center, Los Angeles, CA
Speaker: “Sickle Cell Anemia”, Good News Radio Program, KTYM, Inglewood Ca.
Oncology Lecture: “Use and Administration of Cisplatin Chemotherapy”. St. Francis Medical Center Lecturer: “Lymphoma Overview”. Charles R. Drew College of Medicine and Science.
Speaker-Grand Rounds: “Anemia”. Department of Medicine, Martin Luther King Jr., OutPatient Center.
Speaker: “Risk Factors for Rectal Cancer “. Good News Radio Program.
Speaker: “Cancer Prevention”, Women’s Association of Lynwood. Lynwood, CA.
Speaker: “Palliative Care”, Third Annual End of Life Conference. St. Francis Medical Center.
Speaker: “Medical Futility”, Bioethics Grand Rounds. St. Francis Medical Center.
Speaker: “Hydroxyurea Therapy for Sickle Cell Anemia”. Conference. Charles Drew College of Medicine
and Science.
Speaker: “Treatment of Aids”, Allied Health Students. St. Francis Career College, Lynwood, CA.
Speaker: “Single Payer Health Care System”. Los Angeles County Medical Association, District 10. Speaker: “Proposition 185, California Health Security Act”, Medical Staff Quarterly Meeting.
St Francis Medical Center.

Position: Associate Professor of Clinical and Administrative Sciences (Adjunct/Part-time)

Biography:
Board Certified Oncology Pharmacist with 10+ year experience including supervision, management and working experience in Pharmacy IT Support and Cancer Center Pharmacy Operations. Also experienced in clinical research pharmacy, and expert in Epic Willow inpatient, and Beacon Subject Matter, designed and implemented EPIC Willow Inpt/Beacon pharmacy/nursing workflows for Infusion Centers. With these expertise and experiences, Dr. Hoang has certifications on the following: EPIC Beacon and Willow Inpatient; PMI Certified Project Management Professional with proven experience in leading multiple successful projects; Allscripts Certified in Medical Logic Module, ObjectPlus, and Sunrise Clinical Manager, and Board-Certified Sterile Compounding Pharmacist. Strong knowledge with SQL Report, MS Project, MS Visio, MS Word, MS Excel, MS Access and Tableau BI.

Education:
PG-Y1 Residency Pharmacy Resident (2007): UC Irvine Health Pharmacy Orange, CA
Doctor of Pharmacy (2007): UC San Diego School of Pharmacy, San Diego, CA
Bachelor of Science in Biological Sciences (2000): UC Irvine, Irvine, CA

Areas of Expertise:
IT Medicine Management & Oncology, Pharmacy Informatics, Infusion Center Pharmacist

Pharmacy Practice Experience:
UC Irvine Health Infusion Center Pharmacy Manager: Orange, CA Pharmacy Services
UC Irvine Health Infusion Center Pharmacy Supervisor: Orange, CA Pharmacy Services
UC Irvine Health IT Med Mgmt & Oncology Supervisor: Orange, CA Informational Services
UC Irvine Health Pharmacy Informatics Specialist: Orange, CA Informational Services
UC Irvine Health Infusion Center Pharmacist: Orange, CA Pharmacy Services

Professional Licensure & Certifications
• Advanced Practice Pharmacist APH# 10096: CA Board of Pharmacy
• Registered Pharmacist RPH# 59004: CA Board of Pharmacy
• Board Certified Sterile Compounding Pharmacist Board of Pharmacy Specialty
• Board-Certified Oncology Pharmacist Board of Pharmacy Specialty
• Project Management Professional Project Management Institute
• Certified Professional in Health Information and Management Systems HIMSS
• BLS/ACLS AHA
• EPIC Beacon Certified EPIC
• EPIC Willow Inpatient Certified EPIC
• MLM/ObjectPlus Allscri

Position: Associate Professor of Clinical and Administrative Sciences (Adjunct/Part-time)

Biography:
An experienced Clinical Pharmacist with 35 years in practice with clinical skills in oncology, intensive care unit, trauma, and mental health pharmacy. As oncology pharmacist, Dr. Johnson managed pharmacy technicians in preparation of chemotherapy drugs, storage and distribution, in addition to setting up and managing ICU pharmacy for trauma patients. As pharmacist-in-charge, Dr. Johnson managed pharmacy staff in the mental health inpatient pharmacy.

Education:
Doctor of Pharmacy, 1986. University of Southern California
Bachelor of Arts, Chemistry, 1983. California State University

Areas of Expertise:
Oncology, intensive care unit, trauma, and mental health

Pharmacy Practice Experience:
Oncology Pharmacist
Martin Luther King Hospital
Los Angeles County Department of Health Services, Los Angeles, CA
Clinical Pharmacist
Managed Oncology Pharmacy with preparation of chemotherapy drugs, storage and distribution.

Intensive Care Unit, and Trauma Center Pharmacist
Martin Luther King Hospital
Intensive Care Unit, Trauma Center
Set-up and managed the ICU satellite for trauma patients in the ICU. Responsible for infectious disease on pharmaceutical investigational drugs.

Mental Health Pharmacist
Augustus Hawkins Mental Health Pharmacy
Managed pharmacy staff in the mental health in-patient pharmacy part of the Los Angeles County Department of Health Services.

Position: Associate Professor of Clinical and Administrative Sciences (Adjunct/Part-time)

Biography:
An experienced, driven, and accomplished Pharmacy Professional and Leader, with a wealth of experience while working for leading, high-profile companies. Owner of Dang Pharmacy Group, Inc. experienced in managing operations, profit and loss, staff training and development, auditing for assurance of medication use safety, staff performance evaluation, staff succession planning, regulatory compliance, and handling a wide variety of special projects. Serves as Clinical Pharmacist/Pharmacist in Charge for the San Gabriel Medical Pharmacy and Pharmacist in Charge for San Gabriel Compounding Pharmacy. A proven manager and possesses a firm commitment to the timely provision of the highest levels of pharmacy services and support. Strong background in many areas including pharmacy management, best practices implementation, performance management, and patient relations. Highly-experienced in all aspects of pharmacy management, and is thoroughly familiar with pharmacy and healthcare practices, standards, and protocols. Experienced in all areas of pharmacy management, has managed many high-profile pharmacies, and is proven in meeting the highest in profitability and productivity expectations.

Education:
Doctor of pharmacy, 2003: University of Colorado Health Sciences Center, Denver, Colorado
Certified pharmacy technician, 1998: American Institute of Health Sciences, Long Beach, California
Pre-pharmacy studies: University of California- Irvine, Irvine, California

Areas of Expertise:
Community Practice, Ambulatory Care

Pharmacy Practice Residency Experience:
• Oncology: Preceptor: Shirley Wong, Pharm. D.
• Critical Care Surgical/Trauma: Preceptor: Paul Tan, Pharm.D., FASHP
• Neonatology: Preceptor: Bill Renfro, Pharm.D.
• Internal Medicine: Preceptors: Sharon Basile, Pharm.D., BCPS, Ben Balto, Pharm. D.
• Psychiatry: Preceptor: Elizabeth Eichel, Pharm .D.
• Medical Intensive Care Unit: Preceptor: Andrea Williams, Pharm.D.
• Ambulatory Care: Preceptor: Karen Malcolm, Pharm.D.
• Medical Intensive Care Unit: Preceptor: Peter Liang, Pharm D.
• Departmental Practice Management: Preceptor: Thanh Hogan, Pharm.D.
• Therapeutic Policy Management/Drug Information: Preceptors: Andrea McKeever, Pharm. D.,
Amy Petrehn, Pharm.D.

Clinical Clerkship
• Oncology: Porter Adventist Hospital, Denver, Colorado – Preceptor: Robin Mower, Pharm.D. (2003)
• Community Pharmacy: King Soopers Pharmacy #39, Denver, Colorado – Preceptor: John Kuttler, R.Ph. (2003)
• Adult Medicine: Rose Medical Center, Denver, Colorado – Preceptor: Kevin LeBlanc, Pharm.D. (2003)
• Investigational Drug Research: Centura Health Hospital, Denver, Colorado – Preceptor: Susan Lottimer, Pharm. D. (2002).
• Critical Care Pharmacotherapy: University Hospital, Denver Colorado – Preceptor: Dough Fish, Pharm. D. (2002)
• Ambulatory Care: Kaiser Permanente – East Clinic, Denver, Colorado – Preceptors: Erin Vogel and Katie Peterson, Pharm.D (2002)
• Drug Information: University of Colorado Health Services Center School of Pharmacy, Denver Colorado
Preceptor: Janet Pate, Pharm.D.
• Community Pharmacy: Kaiser Permanente of Colorado-East Clinic, Denver, Colorado-
Preceptor: Bruce Emerson, R.Ph.

Professional Licensure
• Advanced Practice Pharmacist (2016-Present), State of California APH (10195)
• Pharmacist, State of California (2004-Present) RPH (56258)
• Pharmacist, State of Florida (2004-2005) PS (37880)
• Certified Compounding Pharmacist (Since 2013)
• Intern Pharmacist (2000-2004), State of California (10901)
• Intern Pharmacist (2000-2003), State of Colorado
• Pharmacy Technician (1998-1999)

Professional Presentations
• In Service: Urinalysis; Presented to psychiatric nursing staff, Shands Jacksonville Medical Center (2004)
• In-Service: The Use of Xigris, The Use of Pharmacodynamics to Select and Optimize Antimicrobial Therapy, Presented to critical care nursing staff, Shands Jacksonville Medical Center (2004)
• Southeastern Residency Conference: Characterization of Medication Induced Angioedema at Shands Jacksonville (UFJ 2003-0124); presented to pharmacists and pharmacy residents about residency research project that was done at Shands Jacksonville, The University of Georgia, Center for Continuing Education (2004)
• Jacksonville (UFJ 2003-0124); presented to pharmacists and pharmacy residents about residency research project that was done at Shands Jacksonville, The University of Georgia, Center for Continuing Education (2004)
• In-Service: Ventilator-Associated Pneumonia; Presented to critical care physicians, medical residents, pharmacists, pharmacy residents and others; Shands Jacksonville Medical Center (2004)
• Grand Rounds: Palliative Care In Cancer Patients’ Psychological Perspective-Anxiety/Depression; Presented to pharmacists, pharmacy students, and others; Shands Jacksonville Medical Center (2004)
• P&T Meeting: Fulvestrant Monograph; Presented to Pharmacy and Therapeutics Committee for Formulary Review; Shands Jacksonville Medical Center (2004)
• Class Review: Therapeutic Management of Nausea/Vomiting; Presented to Pharmacy and Therapeutics Committee for Formulary Review, Porter Adventist Hospital, Denver, Colorado (2003)
• Leukemia and Tumor Lysis Syndrome; Presented to pharmacists, Porter Adventist Hospital, Denver, Colorado (2003)
• Opportunistic Infections in Post-Renal Transplant; presented to pharmacists and pharmacy students, University of Colorado Health Sciences Center School of Pharmacy, Denver, Colorado (2002)
• Narcotic Potency Comparison and Cross Allergenicity: Presented to pharmacists, Kaiser-Permanente – East Clinic, Denver, Colorado (2002)
• Cancer Cachexia: Presented to pharmacist and pharmacy students, University of Colorado Health Sciences Center School of Pharmacy, Denver, Colorado (2020)
• Drug Inducted Nutrient Depletion: Presented to pharmacists and pharmacy students, Kaiser-Permanente – East Clinic, Denver Coronado (2002)
• Common Mucocutaneous Toxicities Associated with Chemotherapy: Pharm. D. Seminar, presented to faculty and pharmacy students, University of Colorado Health Sciences Center School of Pharmacy, Denver, Colorado (2001)

Research Experience
Characterization of Medication Induced Angioedema at Shands Jacksonville
(UFJ 2003-0124)
Co-Investigators: Amy M. Petrehn, Pharm. D., June McAdams, Pharm. D, Shands Jacksonville Medical Center, Jacksonville, Florida (2003-Present)

Professional Organizations
• California Society of Health System Pharmacists
• American Society of Health System Pharmacists
• Member, Board of Trustees, American University of Health Sciences, Long Beach, California
• American Pharmaceutical Association
• Member, PCCA (Professional Compounding Centers of America
• Member, CPhA (California Pharmacist Association)
• Member, NCPA (National Community Pharmacists Association)

Dr. G.S. Shankar

Professor, Clinical and Administrative Sciences

Bio
Dr. G.S. Shankar Completed his PharmD from Creighton University, Omaha, Nebraska, Master of Science degree from UNC in Public Health, completed Master of Clinical psychology from Calsouthern University and is a PsyD candidate from the same university. He is a registered pharmacist in the state of California and licensed as Advanced Practice Pharmacist as well from the state Board of Pharmacy. He is Fellow of the Australian College of Pharmacy (FACP) and fellows of the Australian college tend to have had training and certification in two clinical specialties and Dr. Shankar completed training and certifications in psychiatry and Geriatrics at the time of the fellowship award. He completed two years of training as a Pharmacist clinician and licensed as pharmacist clinician from New Mexico Board of pharmacy up to 2010.
Recently he completed 5 years of experience as Clinical Pharmacy Specialist-Psychiatry at Veteran’s Out-patient’s Clinic with prescribing privileges at Laredo, Texas. Prior to this he worked as Associate Professor at Western University of Health Sciences, Pomona, California for a period of 13 years and also conducted a successful Psychopharmacology residency program. Prior to his teaching assignment, he worked as treatment review consultant to the department of mental health at Vacaville.

Education
PharmD – Creighton. University, NE
PSY.D (c) – California Southern University, CA
MS (Clinical Psychology) – California Southern University, CA
MS (Public Health) – University of Northern Colorado, CO
Pharm Clinician Training Ph-C Licensure (2 years) at CMF and Psychiatry at MH
Department, Vacaville. Currently licensed as Advanced Practice Pharmacist (CA).

Areas of Expertise: Ambulatory, In-Patient Care, Psychiatry and Neurology, and Clinical Psychology

Courses Taught: Psychiatry and Neurology and Clinical Psychology (for allied professionals)

Scholarship Interests: Research in Psychiatry and Psychology

Publications:
https://www.researchgate.net/profile/Gollapudi_Shankar/contributions

Article Publications

1. Mehgan Hassanzadah, Adib H. Bitar, Nile M. Khanfar, Fadi T. Khasawne, Kabirullah Lutfy, and Gollapudi S. Shankar, *A Retrospective Cohort Study of the Prevalence of Anxiety and Agitation in Schizophrenic Smokers and the Unmet Needs of Smoking Cessation Programs. Journal of Medicine (Dec 2019)

2. Molecular Basis of Neuropsychiatric Disorders: from Bench to Bedside-A Book Chapter for Publication -Progress in Molecular Biology and Translational Research, 2019, Elsevier Series (Sept 2019)

3. Shankar GS (2015) Role of Autacoids in the Development of Vulnerability and Resilience in Patients with Posttraumatic Stress Disorder (PTSD). J Autacoids 4: e126. doi:10.4172/2161-0479.1000e126

4. Khasawneh F and Shankar G, (2014), Minimizing Cardiovascular Adverse Effects of Atypical Antipsychotic Drugs in Patients with Schizophrenia. Cardiology Research and Practice

5. GS Shankar (2014) Serotonergic Projections: Religiosity and Hyper-Religiosity. J Autacoids 3: e123. doi:10.4172/2161-0479.1000e123

6. Shankar GS, Yuan C (2013) Effects of 5HT2c Blockade of Dibenzodiazepines on Thyroid Levels in Patients with Schizophrenia or Schizoaffective Disorder. J Autacoids 2: 102. doi:10.4172/2161-0479.1000102

7. Shankar G (2012) Role of Serotonin from Thought and Anxiety to Weight Gain and Metabolic Syndrome. J Autacoids 1:e118. doi:10.4172/21610479.1000e118

8. Nazer L, Al-Najjar T, Shankar G, “Agranulocytosis Associated with Psychotropic Medications: A Fatal Case”- Literature Survey ‘Journal of American Society of Hospital Pharmacy’ published in July 2012

9. Shankar G. “Clinical Assessment of Substance Abuse” Clinical Knowledge, Research and Therapeutics section, Spring 2010 California Pharmacist

10. Shankar G. ‘Conundrum of Bipolar Depression’, California Journal of Hospital Pharmacy May/June 2008; 18-23.

11. Shankar G, Nate C. “Positive and Negative Syndrome Scale as a long- term outcome measurement tool in patients receiving clozapine ODT- a Pilot Study”. Pharmacy Practice 2007; 5(1): 42-45.

12. Shankar G, Kelly Lee, Jack Chen. Metabolic Adverse Effects of Atypical Antipsychotic Medications. California Pharmacist Spring 2006; 12-17.

13. Jun JK, Shankar G, Shapiro K. The Pharmacology of Pain. California Pharmacist 2003; XLX (3):

Book Chapters

1. Shankar, G and Lutfy, K. Molecular Basis of Neuropsychiatric Disorders: from Bench to Bedside-A Book Chapter for Publication -Progress in Molecular Biology and Translational Research, 2019, Elsiever Series (Sept 2019)
2. Shankar G. “Clinical Psychopharmacology in Correctional settings”, Book: Correctional Mental Health- from Theory to Best Practice, 2010, SAGE Publications, Inc
3. Shankar, G. “Practical Psychopharmacology: What every mental health professional needs to know – Manual for Mental Health Professionals”, Pesi HealthCare. 2007
4. Shankar G, Kelly Lee, Jack Chen. “Metabolic, Endocrinology, and Cardiovascular Adverse Effects of Psychotropic Drugs”, Psychiatry, PSAP Program, Fifth Edition 2004, Volume 3, 163-182

Non-Peer Reviewed

1. Shankar and Yuan, 2010. Monitoring and Counseling of Metabolic Complications and Antipsychotic Pharmacotherapy; Premier Educational Solutions

2. Shankar, 2007. Efficacy of Polypharmacy with Atypical Antipsychotic Medications in Schizoaffective Patients, Prescription Times

Helen Rhee, PharmD
Assistant Professor, Clinical and Administrative Sciences

Education
PharmD – Loma Linda University, School of Pharmacy, Loma Linda, CA
PGY-1 Pharmacy Practice Residency – Dignity Health, St. Joseph’s Medical Center, Stockton, CA
Pharmacy Resident Teaching Certification – University of Pacific, Thomas J. Long School of Pharmacy, Stockton, CA
BS in Biochemistry – University of Nevada, Las Vegas, Las Vegas, NV

Bio
Dr. Rhee obtained her Bachelor of Science in Biochemistry from the University of Nevada, Las Vegas, and received her Doctor of Pharmacy from Loma Linda University in Loma Linda, CA. She completed an ASHP accredited PGY-1 Pharmacy Practice residency at Dignity Health, St. Joseph’s Medical Center in Stockton, CA with an acute care focus, specializing in internal medicine/oncology, infectious disease, emergency services, cardiology, and pharmacokinetics. During her residency training, Dr. Rhee also obtained a pharmacy resident teaching certification at the University of the Pacific, Thomas J. Long School of Pharmacy. She is a member of Phi Lambda Sigma Leadership Society.

Areas of Expertise:
Acute Care Services

Course Taught:
Integrated Pharmacotherapy VI – Infectious Disease

Radhika Venkatraman Kumar, BPharm, MS, PhD
Assistant Professor, Department of Pharmaceutical Sciences

Bio:
Dr. Kumar joined as an Assistant Professor at AUHS in August 2019. Prior to AUHS, Dr. Kumar has gained extensive teaching experience in various institutions in New York. Her research work/interests include drug designing, organic synthesis, and preliminary biological evaluation of potential drug candidates. She also uses molecular modeling software to speculate the possible mechanism of action of the newly synthesized target molecules paving the way for the development of structure activity-based library of compounds.

Education:
B. Pharm, Prin. K.M. Kundnani College of Pharmacy, Mumbai, India
MS (Medicinal Chemistry) – St. John’s University, New York
PhD (Medicinal Chemistry) – St. John’s University, New York

Areas of Expertise:
Organic Synthesis, Computational Modeling

Courses Taught:
Pharmaceutical Calculations
Pharmaceutics and Biopharmaceutics
Introduction to Medicinal Chemistry
Integrated Pharmacotherapy I – Fluid and Electrolyte
Integrated Pharmacotherapy VII – Oncology and Nutrition
Integrated Pharmacotherapy V – Pulmonology and Nephrology

Scholarship/ Research Interests:
Oncology, Infectious disease, Opioid dependence and tolerance, Pharmacy Education

Abstracts/Presentations/Publications:
Kumar, R., V; Yang, S; Dutta, A., P; Islam, M., A.; Medicinal Chemistry Course Offerings by US schools/ Colleges of Pharmacy; AACP, Virtual Pharmacy Education (July 2020)
Islam, M., A; Yang, S; Kumar, R., V; Dutta, A., P; Talukder, R., M.; The Focus of Societal Responsibility in the Mission Statements of US Pharmacy Schools/Colleges; AACP, Virtual Pharmacy
Education (July 2020)
Invited Guest Speaker at an International Seminar “Endeavour in Research & Academics: Need of the hour” scheduled on in United Institute of Pharmacy, Naini, Prayagraj, INDIA (June 2020)
TOPIC OF PRESENTATION: “Synthesis and biological evaluation of enzyme inhibitors as potential anti-cancer drug candidates

“Synthesis and anticancer evaluation of sulfur containing 9-anilinoacridines as topoisomerase II 𝜶 inhibitors”, Charles R. Drew University, Research Seminar Series (June 2020)
Invited Guest Speaker at International Virtual Learning Series titled “Pharmaceutical research and education: Post COVID-19 at Arulmigu Kalasalingam College of Pharmacy, affiliated to The TN.
Dr. M.G.R. R Medical University, Chennai, INDIA (August 2020). TOPIC OF PRESENTATION: “Treatment updates for COVID -19”
Invited Guest Speaker at APP 13th INDO-US VIRTUAL CONFERENCE themed “Trends and Challenges in Pharmaceutical Sciences” at R.J. World College of Pharmacy Education and
Technology, Jakhod, Surajgarh, Rajasthan, India organized by APP Rajasthan State Branch & APP American International Branch. (February 2021)

TOPIC OF PRESENTATION:
Drug Metabolism as Crucial Pharmacokinetic Process

Arjun Dutta, PhD

Dean, School of Pharmacy
Education

PhD in Pharmacy Administration from the Medical College of Virginia, Virginia Commonwealth University
BS degree in Pharmacy from Jadavpur University in India
Bio

Dr. Arjun Dutta holds a BS degree in Pharmacy from Jadavpur University in India. He then completed his PhD in Pharmacy Administration from the Medical College of Virginia, Virginia Commonwealth University. Dr. Dutta specializes in Outcomes Research including the areas of Pharmacoeconomics, Quality of Life, and Epidemiology. Dr. Dutta has published extensively in Pharmacy Education including assessment of the curriculum, student admissions criteria, progression, and retention. Dr. Dutta has been involved in academic pharmacy for the past 22 years and has successfully started three pharmacy programs as a founding administrator in Oregon, New York, and California. His decanal appointments (over 12 years of administrative experience) include serving as the Interim Dean as well as Sr. Associate/Assistant Dean for Academic & Student Affairs at three new colleges of pharmacy. Prior to joining academia, he was an Outcomes Manager at a health economics firm specializing in Phase IV research for pharmaceutical companies. Dr. Dutta has over 71 publications in the form of research articles, abstracts, and book chapters in various peer-reviewed journals and professional meetings. He has received both federal (AHRQ, HRSA) and private funding and has conducted research in the areas of health services and outcomes assessment. Dr. Dutta has also been invited to speak at both national and international meetings.
Arjun enjoys travelling with his wife and two sons and is an avid reader and NFL-fan. He and his wife used to regularly compete in Ballroom Dance competitions.
Publications

1. Islam MA., Talukdar RM., Taheri R., and Dutta A. (2019), “Pharmacy relative to other Health Professionals in IPE: A Bibliometric Study.” Journal of
National Black Nurses Association: JNBNA, 30 Nov. 2019, 30(2):38-43.
2. Lakhman S and Dutta A. (2019), “Endocrine Disruptive Chemicals: Silent poison for human health.” EC Pharmacology and Toxicology. 7.11 (2019): 62-63.
3. Dutta A. (2017) The need to integrate Public Health courses in Health Professions curriculum. [Letter]. JOJ Pub Health 2(1): JOJPH.MS.ID.555576 (2017). Available at: https://juniperpublishers.com/jojph/pdf/JOJPH.MS.ID.555578.pdf
4. Dutta A. (2016) Strategies to Improve Student Learning of Pharmacology in Pharmacy Curriculum. Pharm Pharmacol Int J 4(3): 00076. DOI: 10.15406/ppij.2016.04.00076 Available at: http://medcraveonline.com/PPIJ/PPIJ-04-00076.pdf
5. Chen JJ, Horne KE, Dutta AP (2015) “Faith-Based Colleges and Schools of Pharmacy in the United States: A Taxonomic Survey and Results.” Pharm Pharmacol Int J 2(2): 00019. DOI: 10.15406/ppij.2015.02.00019. Available at: http://medcraveonline.com/PPIJ/PPIJ-02-00019.pdf
6. Addo-Atuah J., Dutta A., Kovera C. (2015), “A Global health Elective Course in a Pharm.D. Curriculum.” American Journal of Pharmaceutical Education: 2014; Volume 78, Issue 10, Article 187. Available online at: http://www.ajpe.org/doi/full/10.5688/ajpe7810187 Accessed February 4, 2015.
7. Miederhoff P., Dutta A., Koomer A. (2013), “The Fungal Meningitis Tragedy: Implications for Pharmacy Education and the Profession.” [Letter]. American Journal of Pharmaceutical Education: 2013; Volume 77, Issue 1, Article 18. Available online at: http://www.ajpe.org/doi/full/10.5688/ajpe77118 Accessed February 14, 2013.
8. St. Onge E., Suda K., Devaud L., Wilson A., Dutta A., Et al. Approaches to Management of Dilemmas by Leaders in Academic Pharmacy. Currents in Pharmacy Teaching and Learning. Apr. 2012: V4 (2):78-83e2.http://www.sciencedirect.com/science/article/pii/S187712971200010X. Accessed March 30, 2012.
9. Dutta A. (2011), “Is There a Need for More Research-based Courses in the PharmD Curriculum?” [Letter]. American Journal of Pharmaceutical Education 2011; 75(5); Article 102. Available online at: http://www.ajpe.org/view.asp?art=aj7505102&pdf=yes
10. Koomer A., Lourdes M., Coronel C., Dutta A., Et. al. A pilot study highlighting differences in pharmacists’ perceptions regarding use of pharamcogenetic information in their profession. Journal of Pharmaceutical Research and Health Care (JPRHC) 2011; Vol. 3, Issue 2: 50-61. http://www.jprhc.in/files/0862.pdf
11. Dutta A., Koomer A. (2011), Survey of new pharmacy schools: insights on structure and planning. Journal of Pharmaceutical Research. 2011:10(1): 34-41.
http://journalofpharmaceuticalresearch.org/index.php/kpc/article/view/89037. Accessed: March 31, 2017.
12. Dutta A. (2010), “Change of the Guard- Are we ready?” [Letter]. American Journal of Pharmaceutical Education 2010; 74(1); Article 16. Available online at: http://www.ajpe.org/view.asp?art=aj740116&pdf=yes&w=n
13. Hailemeskel B., Dutta A., Daftary M, Oluwaranti A, Ayuk-Egbe P, Koomer A, Ellis L et al. A Campus-Community Pharmacy Partnership to Foster Awareness and Utilization of MedlinePlusJournal of American Pharmacists Association May-June 2007; 47(3): 385-389.
14. Ghilzai NK, Dutta A. (2007), “India to Introduce 5-year Doctor of Pharmacy Program” [Letter]. American Journal of Pharmaceutical Education 2007; 71(2); Article 38. Available online at: http://www.ajpe.org/aj7102/aj710238/aj710238.pdf
15. Hailemeskel B., Dutta A., Olagbaju F., Ifelowo O., Koomer A. Demographic Differences and Drug Information Resource Preferences of U.S. Pharmacists. Journal of Pharmaceutical Research. Oct. 2006; Vol.5, No. 4: 104-107.
16. Hailemeskel B., Dutta A., (2006), Daftary M., Ayuk P., Et. al. Relationship between pharmacy technician experience and academic performance- A pilot project. Journal of Pharmaceutical Research. July 2006; Vol.5, No. 3: 65-68.
17. Koomer A., Dutta A., Et. Al. To Grade or Not To Grade: Moving away from Grades. U.S. Pharmacist Student Edition Winter 2006:5-7.
18. Dutta A., (2006), A commentary on stress research in the US. International Journal of Therapy and Rehabilitation. March 2006; v13 (3): 117.
19. Hailemeskel B., Dutta A., and Rose D. (2006), Drug Interactions-Knowledge and attitudes of Hospital Pharmacists. Journal of Pharmaceutical Research. January 2006; Vol. 5, No. 1: 1-5.
20. Dutta A., Oke F., Daftary M., Et al. Geriatric Education in US Schools of Pharmacy. Consultant Pharmacist. 2005; 20(1): 45-51.
21. Dutta A., Pyles M, and Miederhoff P. Stress in Health Professions Students. Journal of National Black Nurses Association. July 2005; 16(1):63-68.
22. Reddy R, Daftary MN, Delapenha RD, Dutta AP, Oliver J, Frederick W., Avascular Necrosis and Protease Inhibitor Therapy: 3 Cases. Journal of the National Medical Association 2005; 97(11): 1543 -1546.
23. Montague M., Nichols S., Dutta A. (2005), Self-Management in African-American women with diabetes. The Diabetes Educator. 2005; v31n5: 700-710.
24. Sansgiry S., Bhosle M., Dutta, A. Predictors of test anxiety in doctor of pharmacy students: An empirical study. Pharmacy Education. June 2005; v5(2):121-129. Available online at: http://journalsonline.tandf.co.uk/app/home/contribution.asp?wasp=23190293b2af41218b49270a7592fcd2&referrer=parent&backto=issue,7,11;journal,1,17;linkingpublicationresults,1:300275,1
25. Wutoh A., Dutta A., et al. Treatment perceptions and attitudes of older HIV-infected adults. Research in Social and Administrative Pharmacy. 2005; 1:60-76.
26. Calrke-Taker V. and Dutta A. African-American men and their reflections and thoughts on Prostate Cancer. Journal of National Black Nurses Assoc. July 2005; 16(1):1-7.
27. Dutta A. (2005), “The FPGEE Curriculum Requirement: An Insurmountable Hurdle?” [Letter]. American Journal of Pharmaceutical Education 2005; 69(5); Article 105. Available online at: http://www.ajpe.org/aj6905/aj6905105/ajpe105.pdf
28. Sansgiry S., Dutta, A., Et al. Predictors of Academic Performance at Two Diverse Universities: Effect of Academic Progression. AJPE. Oct. 2004; 68(4); Article 103. Available online at: http://www.ajpe.org/view.asp?art=aj6804103&pdf=yes
29. Shields K., Dutta A, Daftary M., Et al. NP and CAM education in the US pharmacy schools-Results & Comparisons of two surveys. Journal of Pharmacy Teaching. 2004; 11(2):1-12.
30. Hailemeskel B, Bullard W, Ayuk-Egbe P, Daftary M, Akiyode O, Dutta A, Bernard D, Olusanya O, Keeys C, and Bwayo S. (2004), Selected non-approved use of recombinant human erythropoietin. Part 2 of 2. Advances in Pharmacy. 2004; 2(3):280-288.
31. Bullard W, Hailemeskel B, Ayuk-Egbe P, Daftary M, Akiyode O, Dutta A, Bernard D, Belrhiti S, Eze G, and Keeys C. (2004), Selected non-approved use of recombinant human erythropoietin. Part 1 of 2. Advances in Pharmacy. 2004; 2(2):146-155.
32. Dutta A. In response to the letter entitled, “Pharmacy Graduates from Foreign Countries Flooding US Job Market” [Letter]. AJPE 2004; 68(1), Article 23. Available online at: http://www.ajpe.org/view.asp?art=aj680123&pdf=yes
33. Dutta A., Miederhoff P, and Pyles M. (2003), Complementary & Alternative Medicine Education: Students’ Perspectives. American Journal of Pharmaceutical Education. 2003; 67(2), Article 46. Available online at: http://www.ajpe.org/volsIssues/issueView.asp?vol=67&issue=02
34. Daftary M., Dutta A., Lee E., Olagundoye A., and Xue Z. Patients’ willingness to pay for cognitive pharmacy services in ambulatory care settings in the US. Journal of Pharmacy Practice and Research. 2003 (December); 33: 265-7.
35. Dutta A., Bwayo S, Xue X, Et al. Complementary and Alternative Medicine Instruction in Nursing Curricula. Journal of National Black Nurses Association. Dec. 2003; 14(2):30-33.
36. Dutta A., Daftary M., Ayuk P., and Kang H. State of CAM Education in US Schools of Pharmacy: Results of a National Survey. JAPhA. Jan-Feb. 2003; 43(1):81-83.
37. Bernard D., Dutta A., Daftary M. A descriptive report of bleeding complications secondary to Warfarin Therapy. Hospital Pharmacy 2003; 38(1):36-39
38. Hailemeskel B., Dutta A., and Daftary M. SIAR in a university teaching hospital. American Journal of Health-System Pharmacy Jan. 2003; vol. 60:194-195.
39. Dutta A., Wutoh A., Williams C., and Ofosu J. Predictors of Academic Success at a Historically Black School of Pharmacy. Journal of Pharmacy Teaching 2002; 10(2): 1-14.
40. Dutta A. In response to the letter entitled, “Doctoral Education: A tragedy of the commons” [Letter]. Am. J. Pharmaceutical Education 2002; 66(4):463-464.
41. Hailemeskel B. and Dutta A. A Review of Internet Based Drug Information Resources and Student Preferences. Journal of Social and Administrative Pharmacy. 2002; 19(3):82-86.
42. Hailemeskel B, Ayuk-Egbe P, Akiyode O, Dutta A., Olu Ifelowa, Betton T, Kim M, Dillon E, and Fullas F. The effect of Pharmacist’s Herbal Counseling on Patients’ Knowledge and Satisfaction in a Community Pharmacy. Natural Health Partner; 2002:1(15) (On-line Journal) http://www.imakenews.com/entrails/e_article000078191.cfm
43. Hailemeskel B., Dutta A, Wutoh A., Adverse Reactions and Interactions among Herbal Users. Issues in Interdisciplinary Care, National Academies of Practice, Oct. 2001; V3N4:297-300.

Elaine Nguyen, PharmD, MS

Director, Pharmacy Practice Experience (IPPE)
Assistant Professor, Department of Clinical and Adminsitration Sciences
Education

Doctor of Pharmacy from Western University of Health Sciences.
Master of Science in Health Care Administration from Oklahoma State University.
Bachelor of Science in Biological Sciences from University of California, Irvine.
Bio

Dr. Elaine Nguyen joined AUHS with over 7 years of community practice experience. She received her Doctor of Pharmacy (PharmD) from Western University of Health Sciences, Master of Science in Health Care Administration (MHA) from Oklahoma State University, and Bachelor of Sciences (BS) from University of California, Irvine. Prior to joining AUHS, Dr. Nguyen worked with independent pharmacies in developing and implementing policies and procedures for new clinical programs and regulatory compliance.
Dr. Nguyen is an active community volunteer and promoter of her profession, serving on a number of boards, including Orange County Pharmacists Association, Orange County Prescription Drug Abuse Prevention Coalition, and Vietnamese Pharmacists Association. She is also part of the California Medical Assistance Teams (CAL-MATs), group of highly-trained licensed medical professionals and logisticians organized and coordinated by the State Emergency Medical Services Authority (EMSA) for rapid field disaster medical response. As a CALMAT member, Dr. Nguyen was deployed to assist the state during the Campfire in Paradise, Butte County, California in 2018 and deployed to Sacramento to operationalize various missions throughout California during the COVID-19 pandemic.
Publications and Scholarly Activities

A. PUBLICATIONS (Peer reviewed)
Hata, M PharmD., Shimomura, S PharmD., Nguyen, E PharmD., Hoang, S PharmD Candidate 2018, Nuesa, M PharmD Candidate 2018,. 2017. Medicare Part D Primer. California Society of Health-Systems Pharmacists, Vol.29 No.5: 133-143.

Stanley W. Luong, Stephanie Tran, Amy Ngo, Michael Caulderon, Joyce Fong, Michelle Tran, Elaine Nguyen, Nicholas Do, Sumayya Khan, Edward K. Wong, Jur. MD; A Study of Interleukin Cytokines in the Neurotrophic Keratitis and Keratoconjunctivitis Sicca Animal Model. Invest. Ophthalmol Vis. Sci 2011; 52(14): 3776.

B. PUBLICATIONS (Non-Peer Reviewed)
Nguyen E, Vuong L. Retrospective Analysis of an Outbound Telephonic Medication Adherence Program. Poster Day, Western University of Health Sciences, Pomona, CA, April 2016.

C. MANUSCRIPT REVIEWER
Journal of Pharmacy Practice, 2019 – present

Youngil Chang, PharmD. M.S.

Assistant Professor, Clinical and Administrative Sciences
Education

Doctor of Pharmacy, Palm Beach Atlantic University, FL
M.S. in Chemistry, Seoul National University, South Korea
B.S. in Chemistry, Seoul National University, South Korea
Bio

Dr. Chang received his Doctor of Pharmacy degree from Palm Beach Atlantic University at the west palm beach, FL. After graduation, he joined the graduate research fellowship at Western University of Health Sciences, CA in organ transplantation and pharmacogenomics. During his fellowship he was working with the organ transplant team at St. Vincent Medical Center, Los Angeles for the management of the kidney transplant patients and also performed independent research in pharmacogenomics and antibody mediated rejections on transplanted organ at the HLA laboratory, Los Angeles, which provide essential genetic testing for the transplant donors and recipients. Dr. Chang also had involved in research for drug target identification at Purdue University, IN and anesthesia drug monitoring in animal models at Wester University of Health Sciences, CA. He is interested in improving patient’s outcome through translational research that could be applied in the clinical settings.
Publication

1. K. Choi, Y. Chang, T. Shah, D. Min, Analysis of genetic and clinical risk factors of post-transplant thrombocytopenia in kidney allograft recipients. Transplant Immunology, 55 (2019) 101206.
2. Y. Chang, N. Lemp, J. Cicciarelli, D. Min, R. Naraghi, T. Shah, Detecting Glycosylation of Donor Specific Antibodies (DSA) with Single Antigen Beads., Annal. of Transplantation Research. 1 (2018) p1014-5.
3. Y. Chang, T. Shah, J. Yang, D.I. Min, Association of genetic polymorphisms of angiopoietin-like 4 with severity of posttransplant proteinuria in kidney allograft recipients., Transpl. Immunol. 40
(2017) 35–41.
4. Chang, Y., Shah, T., & Min, D. I. Association of Genetic Polymorphisms of Macrophage Inhibitory Factor (MIF) and B-cell Activation Factor (BAFF) with Donor Specific Antibodies in Kidney Allograft Recipients. 2017. Human immunology Submitted.
5. J.C. Cicciarelli, N.A. Lemp, Y. Chang, M. Koss, K. Hacke, N. Kasahara, K.M. Burns, D.I. Min, R. Naraghi, T. Shah, Renal Transplant Patients Biopsied for Cause and Tested for C4d, DSA, and IgG Subclasses and C1q: Which Humoral Markers Improve Diagnosis and Outcomes? (2017). Epub 2017 Jan 15 ahead of printing.
6. Chang, Y., Shah, T., Min, D. I., & Yang, J. W. Clinical risk factors associated with the post-transplant anemia in kidney transplant patients. Transplant Immunology. 2016, 38, 50–53.

Sukhwinder S. Lakhman, PhD
Associate Professor of Pharmaceutical Science

Education
B.Sc. (Medical), B.Ed., M.Sc. (Life Sciences), M.Phil. (Neuropharmacology), Ph.D. (Neurosciences) Guru Nanak Dev University, Amritsar, Punjab, India.

Bio
Dr. Lakhman has more than 15 years of experience in academic, research and teaching in different schools of pharmacy. After earning his Ph. D. degree from Guru Nanak Dev University, he started working as postdoctoral fellow and later as Instructor/ Research Scientist in the State University of New York (SUNY) at Buffalo School of Pharmacy and Pharmaceutical Sciences. During his tenure at SUNY Buffalo he worked in different areas of Pharmaceutical Sciences. He has also worked in and was a founding faculty of D’Youville College School of Pharmacy prior to joining American University of Health Sciences.

He is reviewer of various peer review Journals such a Pharmacogenomics, Pharmaceutical Research, Biogerontology, etc. He has research expertise in the various area such as Pharmacokinetic, Pharmacodynamics, Molecular Pharmacology and Pharmacogenomics as is apparent from his peer reviewed publications. And has published more than 25 research articles in prestigious journals like Pharmacogenomics, Molecular Pharmacology, Journal of Biological Chemistry, Drug metabolism and Disposition, Journal of Pharmacology and Experimental Therapeutics, Brain research etc. He extends is role beyond teacher to serve as volunteer member in Clean air Coalition, Worked as volunteer in a soap kitchen- “Friends of the Night”, Volunteer in the Great Lakes Consortium etc.

Published Research
Kaur , T., Manchanda, S., Lakhman, S.S. and Kaur, G. (2016). Efficacy of anti-epileptic drugs in treatment of Tumor and its associated Epilepsy: An in vitro Perspective. Annals of Neurosciences 23 (1): 33-43.
Singh,R., Lakhanpa, D., Manchanda, S., Kuma, S., Kaur,T., Lakhman, S.S. and Kaur, G. (2015). Middle age on set short-term intermittent fasting dietary restriction prevents brain function impairments. Biogerontology 16(6) : 775 – 88.
Kaur, G. and Lakhman, S. (2012). Dietary restrictions as a potential intervention to retard age-associated impairments of brain functions. This is in: Thakur, M.K. and Rattan, S.I.S (ed’s) Brain Aging and Therapeutic Interventions, New York, NY. Springer Press.
Lakhman, S. S., Ma, Qing and Morse, G.D., (2009). Pharmacogenomics of CYP3A: Considerations for Human Immunodeficiency Virus Treatment. (Review article) Pharmacogenomics (Future medicine) 10(8):1323- 1339.
Lakhman, S. S. Chen, X., Gonzalez, V.M., Schuetz, E. G and Blanco, J.G. (2007) Functional characterization of the promoter of human carbonyl reductase 1 (CBR1). Role of XRE elements in mediating the induction of CBR1 by ligands of the aryl hydrocarbon receptor. Molecular Pharmacology 72(3): 734-43.
Gonzalez, V.M., Ghosh, D., Lakhman, S. S., Pendyala, L., and Blanco, J.G. (2007). A functional genetic polymorphism on human carbonyl reductase 1 (CBR1 V88I) impacts on catalytic activity and NADPH binding affinity. Drug Metabolism Disposition 35(6):973-80.
Gonzalez, V.M., Lakhman, S. S., Ghosh, D., Pendyala, L., and Blanco, J.G. (2006). Functional characterization of a Non-synonymous Single Nucleotide Polymorphism in Human carbonyl Reductase 1 CBR1V88I). AAPS Pharm Sc, 8(S2):1322.
Gonzalez, V.M., Lakhman, S. S., Forrest, A., Relling, M. V., and Blanco, J.G. (2006). Higher activity of polymorphic NAD(P)H:Quinone oxidoreductase in liver cytosols from blacks compared to whites. Toxicology Letters 164: 249-258.
Lakhman, S. S, Ghosh, D and Blanco, J.G., (2005). Functional Significance of a Natural Allelic Variant of Human Carbonyl Reductase 3 (CBR3). Drug Metabolism Disposition 33(2):254-257.
Bhattacharya, A., Lakhman, S.S. and Singh, S. (2004). Modulation of L-type calcium channels in Drosophila by Pituitary adenylyl cyclase-activating Polypeptide (PACAP) mediated Pathway. J. Biological Chemistry 279 (36)3:7291-37297.
Chandrasekaran, E.V.,Lakhman, S. S., Chawda, R., Piskorz, C.F., Neelamegham, S and Matta,K.L., (2004) Identification of Physiologically Relevant Substrates for cloned Gal: 3-O-Sulfotransferases (Gal3STs) distinct high affinity of Gal3ST-2 and LS180, sulfotransferase for the GLOBO H backbone, Gal3ST-3 for N-Glycan MULTITERMINAL Galβ1,4GlcNAcβ units and 6- SULFO Galβ1,4GlcNAcβ,and Gal3ST-4 for the mucin core-2 Trisaccharide. J. Biological Chemistry 279 (11): 10032-10041.

Albert Nguessan Ngo, PhD
Assistant Professor of Pharmaceutical Sciences

Education
PhD University of Missouri Kansas-City, MO, USA
BS, National Polytechnic Felix Houphouet Boigny, Yamoussoukro, Ivory Coast

Bio
Dr. Ngo serves as an Assistant Professor of Pharmaceutical Sciences at American University of Health Sciences. He holds both a B.S and a PhD degree. He received his doctoral degree in pharmaceutical Science from University of Missouri-Kansas City in May 2018 (UMKC). He also worked at UMKC as a postdoctoral research associate. During his years at UMKC, Dr. Ngo developed skills in analytical chemistry, pharmaceutical data analysis, pharmaceutics, engineering material science, and biotechnology.

In addition, Dr. Ngo conducted research in drug delivery system such as development of a topical anti-HIV/AIDS microbicide. He also developed a safe, versatile oral drug delivery system for poorly water-soluble drugs. For this, he obtained a United State utility patent. Dr. Ngo has volunteered as an American Association Pharmaceutical Scientist (AAPS) abstract screener since 2017. In addition, Dr Ngo received many travel awards to present his work at international meetings. Dr. Ngo published 4 first authored articles including 3 peer reviewed research articles.

Published Research
Ngo AN, Ezoulin MJ, Youm I, & Youan BB (2014) Optimal Concentration of 2,2,2-Trichloroacetic Acid for Protein Precipitation Based on Response Surface Methodology. J Anal Bioanal. Tech. 5(4).
Ngo AN, Ezoulin MJ, Murowchick JB, Gounev AD, & Youan BB (2016) Sodium Acetate Coated Tenofovir-Loaded Chitosan Nanoparticles for Improved Physico-Chemical Properties. Pharm Res 33(2):367-383
Patent, Inventors, Ngo NA, Bi-Botti C. Youan; Formulation for pharmaceutical agents, European patent (WO2016201213A1) and, U.S. patent, PCT US2016/036871, Application#62/173,772
Ngo AN, Danielle Thomas, James Murowchick, Navid J. Ayon, Archana Jaiswal, Bi-Botti “Celestin” Youan1Engineering Fast Dissolving Sodium Acetate Mediated Crystalline Solid Dispersion of Docetaxel (Accepted in, International Journal of Pharmaceutics 04/20/2018)
Research and Areas of Interest
Develop Oral Delivery System for Therapeutic Macromolecules (e.g. Proteins and Nucleic Acid).
Extraction/ Synthesis of New Chemical Entities from Natural Plants for Cancer Therapies
Conduct research on homeless Empowering Learning Program, a health education and intervention program

Suhui Yang, PhD
Assistant Professor of Pharmaceutical Sciences

Education
B.S., Oceanography (Major) and Chemistry (Minor), Pukyong National University, South Korea
M.S., Marine Chemistry, Stony Brook University, New York
Ph.D., Medicinal Chemistry, Chonnam National University, South Korea

Bio
Dr. Suhui Yang obtained her B.S. in Oceanography (major) and Chemistry (minor) from Pukyong National University, South Korea, in 2004 and her M.S. in Marine Chemistry from Stony Brook University, New York, in 2008. She later switched her interest to Medicinal Chemistry and earned her Ph.D. under the guidance of Prof. Won-Jea Cho from Chonnam National University, South Korea, in 2012. Her doctoral research was focused on the design and development of novel small molecule compounds targeting Androgen Receptor, Topoisomerase, or JAK/STAT pathway for treating cancers. In research, she used to apply computational techniques such as virtual screening or molecular docking, synthesize various chemical libraries, and optimize the active compounds.

Dr. Yang moved to the University of Michigan where she conducted research as postdoctoral fellow with Prof. Nouri Neamati, working on synthesis of bioactive small molecule compounds as anti-cancer agents (2013-2017). Dr. Yang joined the faculty of the American University of Health Sciences as an Assistant Professor of Pharmaceutical Sciences, School of Pharmacy, in August 2018. Her current research interests are the design and development of small molecule compounds as chemotherapeutic agents and the use of photoaffinity probes for identification of the molecular targets of small molecules.

Selected Publications
1. J. Han, HW. Lee, Y. Jin, DB. Khadka, S. Yang, X. Li, M. Kim, WJ. Cho, “Molecular design, synthesis, and biological evaluation of bisamide derivatives as cyclophilin A inhibitors for HCV treatment”, Eur. J, Med. Chem., (2020), 188, 112031.
2. S. Xu, Y. Liu, K. Yang, H. Wang, A. Shergalis, A. Kyani, A. Bankhead, S. Tamura, S. Yang, X. Wang, C. Wang, A. Rehemtulla, M. Ljungman, N. Neamati, “Inhibition of protein disulfide isomerase in glioblastoma causes marked downregulation of DNA repair and DNA damage response genes”, Theranostics, (2019), 9, 2282.
3. S. Yang, A. Shergalis, D. Lu, A. Kyani, Z. Lu, M. Ljungman, N. Neamati, “Design, Synthesis, and Biological Evaluation of Novel Allosteric Protein Disulfide Isomerase Inhibitors”, J. Med. Chem., (2019), 62, 3447.
4. A. Kyani, S. Tamura, S. Yang (co-first), A. Shergalis, S. Samanta, Y. Kuang, M. Ljungman, N. Neamati, “Discovery and Mechanistic Elucidation of a Class of Protein Disulfide Isomerase Inhibitors for the Treatment of Glioblastoma”, Chem. Med. Chem., (2018), 13, 164.
5. K. Ramkumar, S. Samanta, A. Kyani, S. Yang, S. Tamura, L. Ziemke, J. Stuckey, S. Li, K. Chinnaswamy, H. Otake, B. Debnath, V. Yarovenko, J. Sebolt-Leopold, M. Ljungman, N. Neamati, “Mechanistic evaluation and transcriptional signature of a Glutathione S-transferase Omega 1 inhibitor”, Nature Comm., (2016), 7, 13084.
6. S. Yang, J. K. R., S. Lim, T. G. Choi, J.-H. Kim, S. Akter, M. Jang, H.-J. Ahn, H.-Y. Kim, M. P. Windisch, D. B. Khadka, C. Zhao, Y. Jin, I. Kang, J. Ha, B.-C. Oh, M. Kim, S. S. Kim, W.-J. Cho, “Structure-Based Discovery of Novel Cyclophilin A Inhibitors for the Treatment of Hepatitis C Virus Infections”, J. Med. Chem., (2015), 58 (24), 9546-9561.
7. C. Zhao, S. H. Yang, D. B. Khadka, Y. Jin, K.T. Lee, W.-J. Cho, “Computer-aided discovery of aminopyridines as novel JAK2 inhibitors”, Bioorg. Med. Chem., (2015), 23, 985-995.
8. D. B. Khadka, H. Woo, S. H. Yang, C. Zhao, Y. Jin, T. N. Le, Y. Kwon, W.-J. Cho, “Modification of 3-arylisoquinolines into 3,4-diarylisoquinolines and assessment of their cytotoxicity and topoisomerase inhibition”, Eur. J, Med. Chem., (2015), 92, 583-607.
9. H. T. M. Van, H. M. Jeong, D. B. Khadka, S. H. Yang, C. Zhao, Y. Jin, K. Y. Lee, Y. Kwon, W.-J. Cho, “Design, synthesis and systematic evaluation of cytotoxic 3-heteroarylisoquinolinamines as topoisomerases inhibitors”, Eur. J, Med. Chem., (2014), 82, 181-194.
10. Y. Jin, D. B. Khadka, S. H. Yang, C. Zhao, W.-J. Cho, “Synthesis of novel 5-oxaprotoberberines as bioisosteres of protoberberines”, Tetrahedron Lett., (2014), 55, 1366-1369.
11. S. H. Yang, C.-H. Song, H. T. M. Van, E. Park, D. B. Khadka, E.-Y. Gong, K. Lee, and W.-J. Cho, “SAR Based Design of Nicotinamides as a Novel Class of Androgen Receptor Antagonists for Prostate Cancer”, J. Med. Chem., (2013), 56 (8), 3414-3418.
12. C.-H. Song, S. H. Yang (co-first), E. Park, S. H. Cho, Eun-Yeung Gong, D. B. Khadka, W.-J. Cho, and K. Lee, “Structure-Based Virtual Screening and Identification of a Novel AR Antagonist”, J. Biol. Chem., (2012), 287 (36), 30769-30780.
13. T. N. Le, S. H. Yang (co-first), D. B. Khadka, S. H. Cho, C. Zhao, W.-J. Cho, “Synthetic approaches to natural antioxidant Benzastatin E, F and G analogues”, Bull. Korean Chem. Soc., (2011), 32 (12), 4309-4315.
14. S. H. Yang, D. B. Khadka, S. H. Cho, H.-K. Ju, K. Y. Lee, K.-T. Lee, W.-J. Cho, “Virtual screening and synthesis of quinazolines as novel JAK2 inhibitors”. Bioorg. Med. Chem., (2011), 19 (2), 968-977.
15. S. H. Yang, H. T. M. Van, T. N. Le, D. B. Khadka, S. H. Cho, K.-T. Lee, E.-S. Lee, Y. B. Lee, C.-H. Ahn, W.-J. Cho, “Development of 3-aryl-1-isoquinolinamines as potent antitumor agents based on CoMFA”, Eur. J. Med. Chem., (2010), 45 (11), 5493-5497.
16. S. H. Yang, H. T. M. Van, T. N. Le, D. B. Khadka, S. H. Cho, K.-T. Lee, H.-J. Chung, S. K. Lee, C.-H. Ahn, Y. B. Lee, W.-J. Cho, “Synthesis, in vitro and in vivo evaluation of 3-arylisoquinolinamines as potent antitumor agents”, Bioorg. Med. Chem. Lett., (2010), 20 (17), 5277-5281.

Mohammed A. Islam, PhD, RPh
Senior Associate Dean for Academic Affairs, Professor

Education
PhD and MPhil (Toyama University, Japan) and BS and MS in Pharmacy (University of Dhaka, Bangladesh)

Bio
Dr. Islam currently serves as the Senior Associate Dean of Academic Affairs and Professor of Pharmaceutical Sciences at the American University of Health Sciences (AUHS) School of Pharmacy. Dr. Islam has more than 20 years of academic research, teaching, pharmacy practice, and administrative experiences. Prior to joining AUHS in February 2019, he served as Assistant Dean of Academic Affairs and Professor of Pharmacology at West Coast University School of Pharmacy.

Dr. Islam went to Toyama University in Japan where he earned MPhil and PhD degrees in Pharmaceutical Sciences. He earned his master’s and bachelor’s degrees in pharmacy from the University of Dhaka, Bangladesh.

Dr. Islam has extensive research experience with more than 30 peer-reviewed journal articles and 55 conference abstracts. His current research interests include pharmacy curriculum, global pharmacy education, and Scholarship of Teaching and Learning (SoTL). Dr. Islam’s research has been published in leading pharmacy education journals and presented at national and international conferences.

Published Research
• Islam MA, Taheri R, McBane S, Talukder R. Faculty assessment of scholarship of teaching and learning among United States pharmacy programs. Currents in Pharmacy Teaching and Learning (in press), 2020.
• Rashid M, Rahman M, Nounou M, and Islam MA. Speed and accuracy of pharmacy students’ response to calculation problems with or without formula prompts. Currents in Pharmacy Teaching & Learning. (in press 2020).
• Islam MA, Bagheri R, Lung L, Park SY, Talukder R. Status of Teaching Certificate Programs Offered by US Colleges and Schools of Pharmacy. Health Professions Education. 6 (1): 105-114, 2020. https://doi.org/10.1016/j.hpe.2019.04.001
• Islam MA, Talukder RM, Taheri R, Dutta A. Pharmacy Relative to Other Health Professions in Interprofessional Education: A Bibliometric Study. J Natl Black Nurses Assoc. 30(2):38-43, 2019.
• Islam MA, Khan SA, Gunaseelan, S, Talukder R. Physician Perceptions of Integrating Pharmacists into Healthcare in Bangladesh. J Pharm Pract and Res (2018). https://doi.org/10.1002/jppr.1401
• Islam MA, Sabnis G, Farris F. The trilayer approach of teaching physiology, pathophysiology, and pharmacology concepts in a first-year pharmacy course: the TLAT model. Adv Physiol Educ. 2017 Sep 1;41(3):395-404, 2017.
• Islam MA, Talukder R, Taheri R, and Blanchard, N. Integration of basic and clinical science courses in US PharmD programs. Am J Pharm Educ. 80 (10) Article 166, 2016.
• Islam MA, Khan SA, Talukder RM. Status of Physiology Education in US Doctor of Pharmacy programs. Adv Physiol Educ. 2016 Dec; 40(4):501-508,
• Islam MA, Chen G, and Talukder RM. Specialty Tracks in PharmD Curricula of US Colleges and Schools of Pharmacy. Currents in Pharmacy Teaching and Learning. 8(6):774-781, 2016.
• Islam MA, Khan SA, Gunaseelan S, and Talukder RM. Specialty education for student pharmacists and PharmD graduates in US Colleges and Schools of Pharmacy. Currents in Pharmacy Teaching and Learning. 8:184-190,
• Islam MA and Schweiger TA. Students’ Perception of an Integrated Approach of Teaching Entire Sequence of Medicinal Chemistry, Pharmacology, and Pharmacotherapeutics Courses in PharmD Curriculum. Journal of Pharmacy Practice. 28(2):220-6, 2015.
• Islam MA, Gunaseelan S, Talukder RM, Khan S. Current Challenges in Pharmacy Education in Bangladesh: A Roadmap for the Future. Currents in Pharmacy Teaching and Learning. 6:730–735, 2014.
• Islam MA, Gunaseelan S, Khan SA. A Research Elective Course on Dietary Supplements to Engage PharmD Students in Primary Literature Evaluation and Scholarly Activity. Journal of Pharmacy Practice 1-8 DOI: 10.1177/0897190013516510; 2014.
• Islam MA, Schmidt RW, Gunaseelan S, Sanchez A. An Update on the Cardiovascular Effects of Quercetin, a Plant Flavonoid. Current Nutrition & Food Science 10:36-48, 2014.
• Islam MA, Schmidt RW, Gunaseelan S, Sanchez A. An Update on the Cardiovascular Effects of Quercetin, a Plant Flavonoid. Current Nutrition & Food Science 10:36-48, 2014.
• Islam MA. An Elective Course on the Basic and Clinical Sciences Aspects of Vitamins and Minerals. Am J Pharm Educ77: Article 17. 2013.
• Downing L and Islam MA (corresponding author). The Use of Calcium Supplements and Cardiovascular Adverse Effects: An Update. Am J Health-Syst Pharm. 70:1132-1139, 2013.
• Islam MA. Cardiovascular effects of green tea catechins: progress and promise. Recent Patents on Cardiovascular Drug Discovery 7: 88-99, 2012.
• Islam MA. Soy Isoflavones and Cardiovascular Health: An Update. Current Nutrition and Food Science 7:108-121, 2011.
• Islam MA. Pharmacological Modulations of Cardiac Ultra-rapid and Slowly Activating Delayed Rectifier Currents: Potential Antiarrhythmic Approaches. Recent Patents on Cardiovascular Drug Discovery, 5: 33-46, 2010.
• DeSantiago J, Islam MA, Ziolo MT, Bers DM, and Pogwizd SM: Arrhythmogenic effects of beta2-adrenergic stimulation in the failing heart are due to enhanced SR Ca load. Circulation Research,
• Despa S, Islam MA, Pogwizd SM, Bers DM: Intracellular [Na+] and Na+pump rate in rat and rabbit ventricular myocytes. J Physiol539: 133-143, 2002.
• Despa S, Islam MA, Pogwizd SM, Bers DM: Intracellular Na+concentration is elevated in heart failure, but Na/K-pump function is unchanged. Circulation;105:2543-2548, 2002.
• Kimura I, Islam MA, Ritsu H, Nojima H, Tezuka Y, and Zhao W: Blood pressure lowering, positive chronotropy and inotropy by the veratrum alkaloids germidine and germerine but negative chronotropy by veratridine in mice. J Asian Natural Product Research, 2: 133-144, 2000.
• Islam MA, Nojima H, and Kimura I: Acetylcholne-induced biphasic effect on the maximum upstroke velocity of action potential in mouse isolated right atria: Interaction with b-adrenergic signaling cascade. Jpn J Pharmacol. 78: 181-190, 1998.
• Islam MA, Nojima H, and Kimura I: Muscarinic M1receptor activation reducesmaximum upstroke velocity of action potential in mouse right atria. Eur J Pharmacol. 346: 227-236, 1998.
• Chowdhury AKA, Islam MA, Rashid A, and Ferdous AJ: Therapeutic potential of the volatile oil of Nigellasativaseeds in monkey model with experimental shigellosis. Phytotherapy Res. 12: 361-363, 1998.
• Kimura I, Islam MA, Nojima H, Mizumoto J, Tezuka Y, Weijie Z: Blood pressure-lowering, positive chronotropic and inotropic effects of the veratrum alkaloids, germidine and germerine in mouse. J of Traditional Medicines, 15: 254-255, 1998.
• Kimura I, Islam MA, and Kimura M: Potentiation by higenamine of the aconitine induced positive chronotropic effect in isolated right atria of mice: The effects of cholera toxin, forskolin and pertussis toxin. Biol Pharm Bull. 19: 1032-1037, 1996.
• Kimura I, Islam MA, and Kimura M.: Cholera toxin accentuates the antagonism by acetylcholine of higenamine-induced positive chronotropy in isolated right atria of mice. Biol Pharm Bull. 18: 1509-11512, 1995.
• Kimura I, Makino M, Takamura Y, Islam MA, and Kimura M: Positive chronotropic and inotropic effects of higenamine and its enhancing action on the aconitine-induced tachyarrhythmia in isolated murine atria. Jpn J Pharmacol. 66: 75-80, 1994.
• Kimura I, Hata Y, Islam MA, and Kimura M: Diabetes mellitus-induced enhancement of prostaglandin F2a-response is inhibited by lipoxygenase-but not cyclooxygenase-inhibitors in mesenteric veins and arteries of mouse and rat. Jpn J Pharmacol. 64: 65-70, 1994.
• Reza S, Khan OF, Islam MA, Rashid A, and Chowdhury AKA: In vitro antibacterial activity of Ipomoea fistulusa. Fitoterapia LXV: 465-466, 1994.

Sandor Szabo, MD, MSc, PhD, MPH, DSc (h.c.)
Professor of Pharmaceutical Sciences

Education
MD, University of Belgrade Medical School
MSc, University of Montreal Medical Faculty
PhD, University of Montreal Medical Faculty
MPH, Harvard School of Public Health

Bio
Sandor Szabo, a Fellow of the American Gastroenterological Association (AGAF), and an External Member of the Hungarian Academy of Sciences: After finishing medical school in Belgrade, obtained MSc & PhD in the institute of Hans Selye (the ‘father of biologic stress’) at the University of Montreal & continued with pathology residency at Harvard Med Sch, Boston, where he became assistant & associate professor. He also obtained an MPH at Harvard School of Public Health, & after 20 years at Harvard, became a professor of pathology & pharmacology at the Medical School of University of California, Irvine (UCI), CA. He also served as chief of Pathology & Laboratory Medicine Service for 20 years, of which for 12 years also covered the functions of chief of staff at the VA Medical Center in Long Beach, CA, where he continued his productive research in the molecular mechanisms of stress-related diseases, esp., gastrointestinal (GI) ulceration. His laboratory was the first to publish easily reproducible, chemically induced duodenal ulcers & adrenal necrosis in rats. This was followed by structure-activity studies (SAS) with chemicals that induce duodenal ulcers which is the most frequent form of peptic ulcers in patients. These SAS led to the first recognition of dopamine in the pathogenesis of duodenal ulceration in animal models & man. Subsequently, he demonstrated for the first time the potent ulcer healing effect of angiogenic growth factors which on molar basis 2-7 million times more potent than antisecretory or anti-H. pylori drugs. His laboratory also published the first gene expression & gene therapy results in duodenal ulceration.

So far, he has 235 original, peer-review publications (several in the best scientific journals like Nature, Science, PNAS, BBRC, JAMA, Lancet, J. Clin. Invest., Lab. Invest., Endocrinology, Gastroenterology, Am. J. Pathol., J. Pharm. Sci., J. Pharmacol. Exp. Ther.), 55 review articles, 37 book chapters, 5 books edited, & 241 invited lectures in North America, Europe, Asia & Australia as well as 9 approved patents, mostly for new GI ulcer drugs & one pending application. In teaching activities, he was course director for general pathology at Harvard Medical School & was teaching GI & endocrine pathology as well as courses in public health & toxicology at Harvard & UCI.

He was associate master at one of the 5 student academic societies at Harvard Medical School (i.e., at Peabody Society) & initiated the establishment of similar student academic societies at UCI to promote small-group teaching & flip classroom techniques. In 2013 he initiated the annual week-long international Summer Schools on Stress (https://www.stresseducation.org ) that has been held at various universities over the world, e.g., Hungary, Croatia, France, Slovakia, Japan & Russia.

Selected Publications
Selye H, Szabo S. Protection by various steroids against gold nephropathy. Eur. J. Toxicol. 1971; 4:512-516.
Szabo S, Selye H. Duodenal ulcers produced by propionitrile in rats. Arch. Pathol. 1972; 93:389-390.
Selye H, Szabo S, Kourounakis P. Protection against phenylisothiocyanate by various steroids, phenobarbital and diphenylhydantoin. J. Pharm. Pharmacol. 1972; 24:333-334.
Selye H, Szabo S. Experimental model for production of perforating duodenal ulcers by cysteamine in the rat. Nature 1973; 244:458-459.
Szabo S, Selye H, Kourounakis P, Taché Y. Comparative studies on the effect of adrenocorticotropic hormone (ACTH) and pregnenolone-16a-carbonitrile (PCN) upon drug response and distribution in rats. Biochem. Pharmacol. 1974; 23:2083-2094.
Kourounakis P, Szabo S, Selye H. Effect of various steroids and ACTH on the distribution of zoxazolamine in rats. J. Pharm. Sci. 1973; 62:1946-1949.
Szabo S, Kourounakis P, Selye H, Da Silva O. Pharmacodynamic interactions among gluco-, mineralo-, glucomineralocorticoids, pregnenolone-16a-carbonitrile and various drugs. J. Pharmacol. Exp. Ther. 1974; 188:45-54.
Szabo S, Komlos S, Ignjatovi_ Z. Effect of pregnenolone-16a-carbonitrile (PCN) on drug response in man. J. Pharm. Pharmacol. 1975; 27:113-118.
Szabo S, Kourounakis P, Selye H. Influence of adrenocorticotropic hormone, somatotrophic hormone and pregnenolone-16a-carbonitrile on drug response and metabolism. Biochem. Pharmacol. 1975; 24:1549-1551.
Szabo S, Reynolds ES, Kovacs K. Animal model of human disease. Waterhouse-Friderichsen syndrome. Animal model: acrylonitrile-induced adrenal apoplexy. Am. J. Pathol. 1976; 82:653-656.
Szabo S, Reynolds ES, Moslen MT. Chemical factors in aetiology of duodenal ulcer. Lancet 1975; 2:73.
Schwedes U, Usadel K, Szabo S. Somatostatin prevents cysteamine-induced duodenal ulcer. Eur. J. Pharmacol. 1977; 44:195-196.
Szabo S. Animal model of human disease. Duodenal ulcer disease. Animal model: cysteamine-induced acute and chronic duodenal ulcer in the rat. Am. J. Pathol. 1978; 93:273-276.
Szabo S, Bailey KA, Boor PJ, Jaeger RJ. Acrylonitrile and tissue glutathione: differential effect of acute and chronic interactions. Biochem. Biophys. Res. Commun. 1977; 79:32-37.
Szabo S, Horvath E, Kovacs K, Larsen PR. Pyrazole-induced thyroid necrosis: a distinct organ lesion. Science 1978; 199:1209-1210.
Szabo S. Dopamine disorder in duodenal ulceration. Lancet 1979; 2:880-882.
Szabo S, Hüttner I, Kovacs K, Horvath E, Szabo D, Horner HC. Pathogenesis of experimental adrenal hemorrhagic necrosis (“apoplexy”). Ultrastructural, biochemical, neuropharmacologic and blood coagulation studies with acrylonitrile in the rat. Lab. Invest. 1980; 42:533-546.
Szabo S, Trier JS, Frankel PW. Sulfhydryl compounds may mediate cytoprotection. Science 1981; 214:200-202.
Szabo S, Reichlin S. Somatostatin depletion in rat organs: a novel effect of the potent duodenal ulcerogen, cysteamine. Endocrinology 1981; 109:2255-2257.
Szabo S, Reynolds ES, Unger SH. Structure-activity relations between alkyl nucleophilic chemicals causing duodenal ulcer and adrenocortical necrosis. J. Pharmacol. Exp. Ther. 1982; 223:68-76.
Palkovits M, Browstein MJ, Eiden LE, Beinfeld MC, Russell J, Arimura A, Szabo S. Selective depletion of somatostatin in rat brain by cysteamine. Brain Res. 1982, 240, 178-180.
Adler RS, Gallagher GT, Szabo S. Duodenal ulcerogens cysteamine and propionitrile decrease duodenal neutralization of acid in the rat. Dig. Dis. Sci. 1983; 28:716-723.
Neumeyer JL, Szabo S. (-)-10,11-Methylenedioxy-N-propylnoraporphine, an orally effective dopamine agonist and duodenal antiulcerogen in the rat. Eur. J. Pharmacol. 1983; 88:273-274.
Gallagher GT, Szabo S. Direct measurement of duodenal acid-pepsin exposure at site of ulceration in rats. Am. J. Physiol. 1984; 246: G660-G665.
Szabo S, Gallagher G, Horner HC, Frankel PW, Underwood RH, Konturek SJ, Brzozowski T, Trier JS. Role of the adrenal cortex in gastric mucosal protection by prostaglandins, sulfhydryls and cimetidine in the rat. Gastroenterology 1983; 85:1384-1390.
Szabo S, Trier JS, Brown A, Schnoor J. Early vascular injury and increased vascular permeability in gastric mucosal injury caused by ethanol in the rat. Gastroenterology 1985; 88:228-236.
Pihan G, Kline TJ, Hollenberg NK, Szabo S. Duodenal ulcerogens cysteamine and propionitrile induce gastroduodenal motility alterations in the rat. Gastroenterology 1985; 88:989-997.
Crum R, Szabo S, Folkman J. A new class of steroids inhibits angiogenesis in the presence of heparin or a heparin fragment. Science 1985; 230:1375-1378.
Szabo S, Brown A, Pihan G, Dali H, Neumeyer JL. Duodenal ulcer induced by MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine). Proc. Soc. Exp. Biol. Med. 1985; 180:567-571.
Szabo S, Horner HC, Maull H, Schnoor J, Chieuh CC, Palkovits M. Biochemical changes in tissue catecholamines and serotonin in duodenal ulceration caused by cysteamine or propionitrile in the rat. J. Pharmacol. Exp. Ther. 1987; 240:871-878.
Silver EH, Szabo S, Cahill M, Jaeger RJ. Time-course studies of the distribution of [1-14C] acrylonitrile in rats after intravenous administration. J. Appl. Toxicol. 1987; 7:303-306.
Szabo S, Rogers C. Diet, ulcer disease, and fish oil. Lancet 1988; 1:119.
Folkman J, Szabo S, Stovroff M. McNeil P, Li W, Shing Y. Duodenal ulcer: discovery of a new mechanism and development of angiogenic therapy that accelerates healing. Ann. Surg. 1991; 214:414-426.
Hauser J, Szabo S. Extremely long protection by pyrazole derivatives against chemically induced gastric mucosal injury. J. Pharmacol. Exp. Ther., 1991; 256:592-598.
Giampaolo C, Gray AT, Olshen RA, Szabo S. Predicting chemically induced duodenal ulcer and adrenal necrosis with classification trees. Proc. Natl. Acad. Sci. USA, 1991; 88:6298-6302.
Szabo S, Folkman J, Vattay P, Morales RE, Pinkus GS, Kato K. Accelerated healing of duodenal ulcers by oral administration of a mutein of basic fibroblast growth factor in rats. Gastroenterology 1994; 106:1106-1111.
Nagy L, Kusstatscher S, Hauschka PV, Szabo S. Role of cysteine proteases and protease inhibitors in gastric mucosal damage induced by ethanol or ammonia in the rat. J. Clin. Invest. 1996; 98:1047-1054.
Szabo S, Vincze A, Sandor Z, Jadus M, Gombo Z, Pedram A, Levin E, Hagar J, Iaquinto G. Vascular approach to gastroduodenal ulceration: new studies with endothelins and VEGF. Dig. Dis. Sci. 1998;4 3:40S-45S.
Khomenko T, Deng XM, Jadus MR, Szabo S. Effect of cysteamine on redox-sensitive thiol-containing proteins in the duodenal mucosa. Biochem. Biophys. Res. Comm. 2003;309:910-916.
Khomenko T, Deng XM, Sandor Zs, Tarnawski AS and S Szabo. Cysteamine alters redox state, HIF-1 transcriptional interactions and reduces duodenal mucosal oxygenation: novel insight into the mechanisms of duodenal ulceration Biochem. Biophys. Res. Commun. 2004; 317(1):121-127.
Deng XD, Szabo S, Jadus MR, Khomenko T, Yoshida M, Herlyn M, Nesbit M, Matsumoto H, Florsheim WH. Gene therapy with naked DNA or adenoviral vector of VEGF or PDGF increases endogenous VEGF, PDGF and bFGF expression and accelerates chronic duodenal ulcer healing in rats. J. Pharmacol. Exp. Ther. 2004; 311:982-988.
Khomenko T, Szabo S, Deng XM, Jadus M, Ishikawa H, Osapay K, Sandor Zs, Chen L. Suppression of early growth response factor– 1 with antisense oligodeoxynucleotide aggravates experimental duodenal ulcers. Am. J. Physiol., Gastrointest. Liver Physiol., 2006; 290:1211-1218.
Sandor Zs, Deng XM, Khomenko T, Tarnawski AS, Szabo S. Altered angiogenic balance in ulcerative colitis: A key to impaired healing? Biochem. Biophys. Res. Commun., 2006; 350:147-150.
Ozdemir V, Jamal MM, Osapay K, Jadus MR, Sandor Z, Hashemzadeh M, Szabo S. Cosegregation of gastrointestinal ulcers and schizophrenia in a large national inpatient discharge database: revisiting the “brain-gut axis” hypothesis in ulcer pathogenesis. J. Investig. Med. 2007; 55(6):315-20.
Deng X, Szabo S, Khomenko T, Jadus MR, Yoshida M, Chen L. Detection of duodenal ulcer-associated genes in rats. Dig. Dis. Sci. 2008; 53(2): 375-84.
Tolstanova G, Khomenko T, Deng XM, Chen L, Tarnawski A, Ahluwalia A, Szabo S, Sandor Z. Neutralizing anti-VEGF antibody reduces severity of experimental ulcerative colitis in rats. Direct evidence for the pathogenic role of VEGF. J. Pharmacol. Exp. Ther. 2009; 328:749-757.
Khomenko T, Szabo S, Deng XM, Ishikawa H, Anderson G J, McLaren GD. Role of iron in the pathogenesis of cysteamine-induced duodenal ulceration in rats. Am. J. Physiol. Gastrointest. Liver Physiol. 2009; 296: G1277-1286.
Deng XM, Tolstanova G, Khomenko T, Chen LC, Tanarwski AS, Szabo S, Sandor Zs. Mesalamine restores angiogenic balance in experimental ulcerative colitis by reducing expression of endostatin and angiostatin: Novel molecular mechanism for mesalamine’s therapeutic action. J. Pharmacol. Exp. Ther. 2009; 331:1071-1078.
Tolstanova G, Deng XM, Khomenko T, Garg P, Paunovic B, Chen LC, Sitaraman SV, Shiloach J, Szabo S, Sandor Zs. Role of anti-angiogenic factor endostatin in the pathogenesis of experimental ulcerative colitis. Life Sci. 2011; 88: 74-81.
Florkiewicz RZ, Ahluwalia A, Sandor Z, Szabo S, Tarnawski AS. Gastric mucosal injury activates bFGF gene expression and triggers preferential translation of high molecular weight bFGF isoforms through CUG-initiated, non-canonical codons. Biochem. Biophys. Res. Commun. 2011; 409:494-499.
Deng XM, Szabo S, Khomenko T, Xiong XM, Sandor Zs, Osapay K, Jadus MR, Tolstanova G, Shiloach J, Chen L. Inappropriate angiogenic response as a novel mechanism of duodenal ulceration and impaired healing. Dig. Dis. Sci. 2011; 56:2792-801.
Tolstanova G, Deng XM, French S, Lungo W, Paunovic B, Khomenko T, Ahluwalia A, Kaplan T, Dacosta-Iyer M, Tarnawski A, Szabo S, Sandor Zs. Early endothelial damage and increased colonic vascular permeability in the development of experimental ulcerative colitis in rats and mice. Lab. Invest. 2012; 92:9-21.
Paunovic B, Deng XM, Khomenko T, Ahluwalia A, Tolstanova G, Tarnawski A, Szabo S, Sandor Z. Molecular mechanisms of bFGF effect on healing of ulcerative colitis in rats. J. Pharmacol. Exp. Ther. 2011; 339:430-437.
Khomenko T, Kolodney J, Pinto JT, McLaren GD, Deng X, Chen L, Tolstanova G, Paunovic B, Krasnikov BF, Hoa N, Cooper AJ, Szabo S. New mechanistic explanation for the localization of ulcers in the rat duodenum: role of iron and selective uptake of cysteamine. Arch. Biochem. Biophys. 2012; 525:60-70.
Ahluwalia A, Jones MK, Deng XM, Sandor Zs, Szabo S, Andrzej S Tarnawski AS. An imbalance between VEGF and endostatin underlies impaired angiogenesis in gastric mucosa of aging rats. Am. J. Physiol. Gastrointest. Liver Physiol. 2013; 305: G325-332.
Khomenko T, Deng X, Ahluwalia A, Tarnawski T, Khushin P, Sandor Zs, Szabo S. STAT3 and importins are novel mediators of early molecular and cellular responses in experimental duodenal ulceration in rats and egr-1 knockout mice. Dig. Dis. Sci. 2014; 59:297-306.
Tolstanova G, Deng X, Ahluwalia A, Paunovic B, Prysiazhniuk A, Ostapchenko L, Tarnawski A, Sandor Z, Szabo S. Role of dopamine and D2 dopamine receptor in the pathogenesis of inflammatory bowel disease. Dig. Dis. Sci. 2015; 60:2963-2975.
Satoh H, Szabo S. A mutein of human basic fibroblast growth factor TGP-580 accelerates colonic ulcer healing by stimulating angiogenesis in the ulcer bed in rats. J. Physiol. Pharmacol. 2015; 66:719-729.
Szabo S, Yoshida M, Filakovszky J, Juhasz Gy. “Stress” is 80 years old: From Hans Selye original paper in 1936 to recent advances in GI ulceration. Curr. Pharm. Des. 2017; 23:4029-4041.
Szabo S. New developments in cell & tissue injury: Focus on PD-1, C1orf106 gene, cell junctions & IBD. Dig. Dis. Sci. 2018 (in press)

John V. Schloss, PhD

Chair of Pharmaceutical Science/Associate Dean of Research, Professor
Education

BS (University of Tulsa, 1973), PhD (University of Tennessee-Knoxville/Oak Ridge National Laboratory, 1978), NIH Postdoctoral Fellow-University of Wisconsin-Madison, 1978-81
Bio

Dr. Schloss brings a perspective on pharmacy education to AUHS based on 10 years as a professional scientist in DuPont’s Central Research Department; 9 years as Professor at the University of Kansas, School of Pharmacy; 6 years in pharmacy-related biotech; and 10 years helping to build the basic science and research components of two domestic and one foreign pharmacy programs. He has remained active in both research and the education of graduate and undergraduate students, while securing research funding from international, federal, state, and private sources. Dr. Schloss was an NIH-postdoctoral fellow at the University of Wisconsin in Madison and holds a Ph.D. in Biomedical Sciences from the University of Tennessee for work conducted at the Oak Ridge National Laboratory.